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Prevention study for Cardiovascular Disease
Official title Recombinant Herpes Zoster Vaccine for Prevention of Cardiovascular Events and Dementia
ClinicalTrials.gov ID: NCT07485283
What this study is testing
What is Recombinant Herpes Zoster Vaccine (Shingrix)?
Recombinant Herpes Zoster Vaccine (Shingrix) is an investigational medicine, given as an injection into a muscle, being studied as a potential treatment for cardiovascular disease.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- DAN-ZOSTER is a nationwide randomized study investigating whether vaccination against herpes zoster (shingles) can reduce the risk of cardiovascular disease and dementia in older adults. Herpes zoster is caused by reactivation of the varicella-zoster virus and becomes more common with increasing age.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 65 and older. Healthy volunteers may be eligible.
You may be able to join if
- Age 65 years and above at the time of consent
- Self-reported ability to understand written and spoken Danish or English
- Informed consent form has been signed and dated
You likely can't join if
- The study has the following exclusion criteria which will be assessed through self-reporting:
- A prior diagnosis of dementia
- Chronic inflammatory rheumatic disease and concomitant immunosuppressive therapy
- Prior herpes zoster vaccination
The study team makes the final eligibility decision.
Where it's taking place
- Hellerup, Denmark
- Søborg, Denmark
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 65 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hellerup, Denmark; Søborg, Denmark. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.