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Compares treatment options for Cardiovascular Diseases (CVD)
Official title The Effects of a 6-week Pre-operative Administration of a Microbiome Modulator "WellBiome" Versus Placebo on Cardiac Surgical Outcomes and NHS Cost Savings.
ClinicalTrials.gov ID: NCT07483502
What this study is testing
- What it's testing
- More than 7.4 million people in the UK are currently waiting for surgery. Behind that number are real people-patients preparing mentally and physically for procedures ranging from joint replacements to major heart and abdominal operations.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 50 to 80
You may be able to join if
- Aged 50-80
- BMI ≥ 25-40kg/m²
- Waist circumference \>94cm (men) and 88cm (women)
- HbA1c 42-58 mmol/mol (6.0-7.5 old HbA1c units)
- No known intolerances to oligosaccharides and xylooligosaccharides
You likely can't join if
- Active cancer
- Any gastro-intestinal surgery or currently under the care of the GI clinical team for any clinically significant digestive issue (Crohn's, IBS...
- On or had antibiotic treatment in the last 3 months.
- Patients who have taken ibuprofen in the last week or any condition that increases the likelihood of regular or sustained use during the intervention.
- On proton pump inhibitors (Omeprazole, Esomeprazole, Lansoprazole, Rabeprazole, Pantoprazole) within the last one month on long acting non-steroidal...
- Taking any prebiotic or probiotic supplementation within the last three months
See the full eligibility criteria
- Aged 50-80
- BMI ≥ 25-40kg/m²
- Waist circumference \>94cm (men) and 88cm (women)
- HbA1c 42-58 mmol/mol (6.0-7.5 old HbA1c units)
- No known intolerances to oligosaccharides and xylooligosaccharides
- Be stable dose of cholesterol and blood pressure medication for 3 months
- Be willing to participate and sign to that effect.
- Active cancer
- Any gastro-intestinal surgery or currently under the care of the GI clinical team for any clinically significant digestive issue (Crohn's, IBS, ulcerative colitis).
- On or had antibiotic treatment in the last 3 months.
- Patients who have taken ibuprofen in the last week or any condition that increases the likelihood of regular or sustained use during the intervention.
- On proton pump inhibitors (Omeprazole, Esomeprazole, Lansoprazole, Rabeprazole, Pantoprazole) within the last one month on long acting non-steroidal anti-inflammatory drugs in the last month or any condition that...
- Taking any prebiotic or probiotic supplementation within the last three months
- Patients who are vegetarians or vegans
The study team makes the final eligibility decision.
Where it's taking place
- Hull, East Riding Of Yorkshire, United Kingdom
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 50 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hull, East Riding Of Yorkshire, United Kingdom. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.