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New treatment option for Non-Small Cell Lung Cancer
Official title Progel Platinum for Air Leak Reduction After VATS Lobectomy for NSCLC
ClinicalTrials.gov ID: NCT07479277
What this study is testing
- What it's testing
- This multicenter randomized trial evaluates whether routine use of Progel Platinum surgical sealant on stapled fissure lines during VATS upper or lower lobectomy for NSCLC reduces pleural drainage duration compared with standard stapling alone. Secondary objectives include postoperative length of stay, incidence and duration of postoperative air leaks, residual pleural space, safety outcomes, and hospitalization costs.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 99
You may be able to join if
- Age ≥18 years
- Written informed consent
- Planned VATS upper or lower lobectomy for NSCLC
- Minimally invasive thoracoscopic approach
- Middle lobectomy excluded
You likely can't join if
- Induction radiochemotherapy or chemo-immunotherapy
- Severe COPD: GOLD 3 or higher
- Sleeve resection or extended resection involving other lobes/chest wall/pericardium, etc.
- Albumin intolerance/allergy
- Renal insufficiency
- Redo surgery
See the full eligibility criteria
- Age ≥18 years
- Written informed consent
- Planned VATS upper or lower lobectomy for NSCLC
- Minimally invasive thoracoscopic approach
- Middle lobectomy excluded
- Induction radiochemotherapy or chemo-immunotherapy
- Severe COPD: GOLD 3 or higher
- Sleeve resection or extended resection involving other lobes/chest wall/pericardium, etc.
- Albumin intolerance/allergy
- Renal insufficiency
- Redo surgery
- Use of sealants/adhesives other than the study approach
- Expected extensive pleural adhesions
The study team makes the final eligibility decision.
Where it's taking place
- Candiolo, Torino, Italy
- Bolzano, Italy
- Florence, Italy
- Milan, Italy
- Palermo, Italy
- Pisa, Italy
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 99 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Candiolo, Torino, Italy; Bolzano, Italy; Florence, Italy; Milan, Italy; Palermo, Italy; Pisa, Italy. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.