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New treatment option for Linezolid
Official title Linezolid Tolerance During the BPaL Regimen With Dosage Personalization Based on Therapeutic Drug Monitoring (TDM) During Multidrug-Resistant Tuberculosis Treatment
ClinicalTrials.gov ID: NCT07477119
What this study is testing
What is Linezolid dose personalization based on TDM?
Linezolid dose personalization based on TDM is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for linezolid.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Multidrug-resistant tuberculosis (MDR-TB) poses a significant challenge to global public health. Globally, the World Health Organization (WHO) estimates the number at 400,000 patients with MDR-TB for 2023.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 15 and older
You may be able to join if
- 1\. Confirmed diagnosis of MDR-TB
- 2\. Linezolid prescribed as part of the BPaL/BPaL-M regimen
- 3\. Age 15 years or older
- 4\. Informed consent obtained from the participant or assent from the parent/legal guardian for participants under 18 years of age.
You likely can't join if
- 1\. Pregnancy or breastfeeding
- 2\. Severe liver or kidney failure
- 3\. Known hypersensitivity to linezolid
- 4\. Concomitant use of medications with drug interactions potential with linezolid
The study team makes the final eligibility decision.
Where it's taking place
- Conakry, Guinea
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 15 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Conakry, Guinea. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.