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Compares treatment options for Hand Injuries and Disorders
Official title Perineural vs Intravenous Dexamethasone as an Adjuvant to Brachial Plexus Block in Pediatric Hand Surgery
ClinicalTrials.gov ID: NCT07474909
What this study is testing
What is iv dexamethasone?
iv dexamethasone is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for hand injuries and disorders.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This clinical trial will evaluate the neurological safety and analgesic effectiveness of dexamethasone administered perineurally or intravenously as an adjuvant to brachial plexus block in children undergoing hand or forearm surgery. Dexamethasone is commonly used to prolong the duration of regional anesthesia, but there is limited evidence on long-term neurological safety, particularly in pediatric patients.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 3 to 16
You may be able to join if
- Age 3 months to 16 years
- Scheduled elective hand or forearm surgery under general anesthesia with a brachial plexus block
- ASA physical status I-III
- Planned use of ultrasound-guided regional anesthesia
- Written informed consent from parent(s) or legal guardian and age-appropriate assent from the child
You likely can't join if
- Pre-existing neurological disease or peripheral neuropathy
- Preoperative sensory deficit in the operative limb
- Infection at or near the needle insertion site
- Coagulopathy or therapeutic anticoagulation
- Systemic infection or sepsis
- Chronic steroid therapy within 30 days before surgery
See the full eligibility criteria
- Age 3 months to 16 years
- Scheduled elective hand or forearm surgery under general anesthesia with a brachial plexus block
- ASA physical status I-III
- Planned use of ultrasound-guided regional anesthesia
- Written informed consent from parent(s) or legal guardian and age-appropriate assent from the child
- Pre-existing neurological disease or peripheral neuropathy
- Preoperative sensory deficit in the operative limb
- Infection at or near the needle insertion site
- Coagulopathy or therapeutic anticoagulation
- Systemic infection or sepsis
- Chronic steroid therapy within 30 days before surgery
- Known allergy to ropivacaine or dexamethasone
- Diabetes mellitus
- BMI \> 99th percentile for age and sex.
- Pregnancy or breastfeeding
- Participation in another treatment clinical trial within 30 days
- Refusal of consent
The study team makes the final eligibility decision.
Where it's taking place
- Poznan, Poland
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 3 months to 16 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Poznan, Poland. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.