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New treatment option for Cardiac Surgery Patient
Official title Effect of Intraoperative Morphine on Postoperative Pain After CABG
ClinicalTrials.gov ID: NCT07472959
What this study is testing
What is In this study, morphine administration, which is routinely and frequently used in our operating room for patients undergoing CABG, was applied as an additional intervention?
In this study, morphine administration, which is routinely and frequently used in our operating room for patients undergoing CABG, was applied as an additional intervention is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for cardiac surgery patient.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Ethics committee approval was obtained for this study, which was planned as a prospective, randomized, controlled, single-center trial to be conducted in patients undergoing coronary artery bypass grafting (CABG) surgery between December 2025 and March 2026. Patients eligible for inclusion were randomized into two groups at a 1:1 ratio using a random number list generated via the random.org website.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- patients aged 18 to 80 years
- classified as American Society of Anesthesiologists (ASA) III
- who are scheduled for elective coronary artery bypass grafting.
You likely can't join if
- Chronic opioid use.
- Severe liver or kidney disease.
- History of alcohol or substance abuse.
- Left ventricular ejection fraction below 40%.
- Inability to be weaned from mechanical ventilation within 12 hours after completion of surgery.
- Undergoing combined cardiac surgery, including valve procedures.
See the full eligibility criteria
- patients aged 18 to 80 years
- classified as American Society of Anesthesiologists (ASA) III
- who are scheduled for elective coronary artery bypass grafting.
- Chronic opioid use.
- Severe liver or kidney disease.
- History of alcohol or substance abuse.
- Left ventricular ejection fraction below 40%.
- Inability to be weaned from mechanical ventilation within 12 hours after completion of surgery.
- Undergoing combined cardiac surgery, including valve procedures.
- Requirement for intra-aortic balloon pump (IABP) support.
- Surgery performed on a beating heart.
- Emergency surgery.
- Reoperation due to bleeding or other complications.
- Refusal to participate in the study.
The study team makes the final eligibility decision.
Where it's taking place
- Istanbul, Outside of the US, Turkey (Türkiye)
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Istanbul, Outside of the US, Turkey (Türkiye). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.