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New treatment option for Acute Kidney Injury
Official title Effects of Creatine Supplementation on Cognitive Measures and Markers of Acute Kidney Injury After Exercise in the Heat
ClinicalTrials.gov ID: NCT07472426
What this study is testing
- What it's testing
- The goal of this clinical trial is to learn if one week of creatine monohydrate supplementation alters inflammation, markers of acute kidney injury (AKI) risk, and cognitive performance in active, young, healthy volunteers. The main questions it aims to answer are: 1.
- You might receive a placebo (an inactive treatment) instead of the study drug. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 45. Healthy volunteers may be eligible.
You may be able to join if
- Age range: 18-45 years old
- Physical Activity Level: Classified as 'active' using the criteria of engaging in planned exercise at least 3x/week, for a minimum of 30 minutes per...
- Aerobic Fitness Level: people must have an aerobic fitness classification of at least 'good' per American College of Sports Medicine (ACSM) criteria...
- Health Status: Free of any known cardiovascular, metabolic, renal, or neurologic conditions.
- Physical Limitations: Indicates no physical limitations to cycling for \~ 90 minutes
You likely can't join if
- Known allergy to creatine or maltodextrin.
- History of adverse heat-related events (e.g., heat exhaustion, heat stroke, severe dehydration requiring medical intervention)
- Reports use of medications or supplements that may interfere with thermoregulation, heart rate, kidney injury or blood pressure responses during...
See the full eligibility criteria
- Age range: 18-45 years old
- Physical Activity Level: Classified as 'active' using the criteria of engaging in planned exercise at least 3x/week, for a minimum of 30 minutes per session, over the past 3 months
- Aerobic Fitness Level: people must have an aerobic fitness classification of at least 'good' per American College of Sports Medicine (ACSM) criteria and assessed via maximal oxygen uptake test
- Health Status: Free of any known cardiovascular, metabolic, renal, or neurologic conditions.
- Physical Limitations: Indicates no physical limitations to cycling for \~ 90 minutes
- Supplementation: Reports no use of creatine within the past 4 weeks
- Recent Illness: Reports no presence of illness, vomiting, or diarrhea in the previous three days.
- Known allergy to creatine or maltodextrin.
- History of adverse heat-related events (e.g., heat exhaustion, heat stroke, severe dehydration requiring medical intervention)
- Reports use of medications or supplements that may interfere with thermoregulation, heart rate, kidney injury or blood pressure responses during exercise (e.g. NSAID)
The study team makes the final eligibility decision.
Where it's taking place
- Cedar Falls, Iowa, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 45 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Cedar Falls, Iowa, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.