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New treatment option for Endometriosis
Official title Pesticides and Infertility: Oxidative Stress Via Circulating Cell-free DNA and Gut/Genital Microbiome Signatures in Women With Endometriosis
ClinicalTrials.gov ID: NCT07471373
What this study is testing
What is Circulating DNA analysis?
Circulating DNA analysis is an investigational medicine, being studied as a potential treatment for endometriosis.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This project PestiEndoMicro aims to provide an innovative approach, studying endometriosis under the genital and gut microbiota scope. To realize this project, the investigators are planning to dose cfDNA to assess the oxidative stress caused by endometriosis and study its epigenetics.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 43, women only. Healthy volunteers may be eligible.
You may be able to join if
- The "case" group will include:
- All women aged 18 to 43, with confirmed endometriosis and endometriosis grade 3 or 4 as defined by the 1985 revised version of the American Society...
- The "control" group will include:
- All women aged between 18 and 43, whose infertility problem is proven male infertility and who do not have endometriosis identified by biological...
- The following criteria will apply to both groups:
You likely can't join if
- All women aged 44 and over.
- Women who are overweight, obese or anorexic.
- Women taking antibiotics 3 months prior to inclusion, or participating in a drug study.
- All women under anti-GnRH treatment, pregnant or suffering from a chronic inflammatory disease such as Crohn's disease, polycystic ovary syndrome...
- All women whose endometriosis has not been formally confirmed by the tests offered by the Reproductive Medicine and Biology Department, CECOS de...
- All patients under guardianship, curators or safeguard of justice.
See the full eligibility criteria
- The "case" group will include:
- All women aged 18 to 43, with confirmed endometriosis and endometriosis grade 3 or 4 as defined by the 1985 revised version of the American Society of Reproductive Medicine.
- The "control" group will include:
- All women aged between 18 and 43, whose infertility problem is proven male infertility and who do not have endometriosis identified by biological, genetic and clinical tests.
- The following criteria will apply to both groups:
- All women who have not received antibiotic treatment in the three months preceding inclusion and who are not participating in any pharmacological study.
- All women who are covered under the national social security health insurance scheme.
- All women who have signed a written informed consent form, thereby confirming their participation in the study after a period of free and informed reflection.
- All women aged 44 and over.
- Women who are overweight, obese or anorexic.
- Women taking antibiotics 3 months prior to inclusion, or participating in a drug study.
- All women under anti-GnRH treatment, pregnant or suffering from a chronic inflammatory disease such as Crohn's disease, polycystic ovary syndrome, etc.
- All women whose endometriosis has not been formally confirmed by the tests offered by the Reproductive Medicine and Biology Department, CECOS de Picardie, CHU Amiens-Picardie.
- All patients under guardianship, curators or safeguard of justice.
- All patients who have not signed the written consent confirming their participation in the study, after a period of free and informed reflection.
- Any patient who withdraws her consent for participation in the study.
The study team makes the final eligibility decision.
Where it's taking place
- Salouël, France
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18 years to 43 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Salouël, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.