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Official title L-serine and Strength Training in the Elderly

ClinicalTrials.gov ID: NCT07466290

What this study is testing

What it's testing
This study investigates whether taking the amino acid L-serine, either alone or in combination with targeted strength training, can have a positive effect on mental performance, brain function, and physical fitness in older people. Healthy, independent women and men aged 65 to 85 are eligible to participate.
  • Time commitment: about 48 weeks
  • You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 65 to 85. Healthy volunteers may be eligible.

You may be able to join if

  • Men and women between the ages of 65 and 85
  • Mini-Mental-State \>23
  • Independently mobile, without aids (walker, cane, etc.)

You likely can't join if

  • Chronic diseases that contraindicate medical training therapy
  • Regular strength training (\>1x/week) in the last 6 months before confinement
  • Frailty Index ≥ 3
  • Lack of written consent to test physical performance
  • Regular use of Cortison-containing medications or Antibiotika
  • MR-specific exclusion criteria: claustrophobia, metal equipment or other magnetic Material in or on the body
See the full eligibility criteria
Who can join
  • Men and women between the ages of 65 and 85
  • Mini-Mental-State \>23
  • Independently mobile, without aids (walker, cane, etc.)
What rules you out
  • Chronic diseases that contraindicate medical training therapy
  • Regular strength training (\>1x/week) in the last 6 months before confinement
  • Frailty Index ≥ 3
  • Lack of written consent to test physical performance
  • Regular use of Cortison-containing medications or Antibiotika
  • MR-specific exclusion criteria: claustrophobia, metal equipment or other magnetic Material in or on the body
  • Non-compliance with the study protocol: \<70% of the planned L-serine administration, \<70% of the strength training

The study team makes the final eligibility decision.

Where it's taking place

  • Vienna, State of Vienna, Austria

Compensation & support

Compensation mentioned.

ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.

Questions & answers

Do participants get paid in this trial?

This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.

How long does this study last?

The study runs about 48 weeks per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.

Who can join this trial?

This study is enrolling all sexes, 65 years to 85 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.

Where is this trial taking place?

Study sites include Vienna, State of Vienna, Austria. Enter your location above to see the nearest site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.