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New treatment option for Postoperative Pulmonary Complications (PPCs)
Official title Postoperative High-flow Nasal Oxygenation After High-risk Surgery in the Frail Adult
ClinicalTrials.gov ID: NCT07464730
What this study is testing
What is High Flow Oxygen?
High Flow Oxygen is an investigational medicine, being studied as a potential treatment for postoperative pulmonary complications (ppcs).
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- High flow nasal oxygen (HFNO) in the immediate postoperative period has been demonstrated to reduce the risk of postoperative pulmonary complications (PPC) after cardiothoracic surgery. In specific groups of patients such as the obese and after upper abdominal surgery the results are contradictive.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Adults (≥18 years old) scheduled for elective abdominal (laparotomy or laparoscopy), open abdominal vascular or non-cardiac thoracic surgery under...
- Age \> 65 years
- BMI \>30
- Preoperative SpO2 \<95 %
- Scheduled for lobectomy or pulmonary segment resection
You likely can't join if
- Not suitable for postoperative HFNO, as decided by a study member or the anaesthetist in charge (such as total nasal obstruction, skull fracture...
- Pregnancy
- Not able to understand the study information or sign an informed consent.
- Not able to participate with the treatment postoperatively
- Planned for delayed extubation in the intensive care
- Preoperative non-invasive ventilation due to respiratory failure or a higher level of care than a regular ward
See the full eligibility criteria
- Adults (≥18 years old) scheduled for elective abdominal (laparotomy or laparoscopy), open abdominal vascular or non-cardiac thoracic surgery under general anaesthesia with an estimated duration over 3 hours. AND Meeting...
- Age \> 65 years
- BMI \>30
- Preoperative SpO2 \<95 %
- Scheduled for lobectomy or pulmonary segment resection
- Respiratory tract infection the last month
- Preoperative anaemia (Hb \<100) or severe hypoalbuminemia (\<20 g/L)
- Current smoker or previous smoker with \>30 packyears
- Pulmonary disease or OSAS
- Heart failure
- Clinical frailty (CFS 4)
- Not suitable for postoperative HFNO, as decided by a study member or the anaesthetist in charge (such as total nasal obstruction, skull fracture, facial injuries)
- Pregnancy
- Not able to understand the study information or sign an informed consent.
- Not able to participate with the treatment postoperatively
- Planned for delayed extubation in the intensive care
- Preoperative non-invasive ventilation due to respiratory failure or a higher level of care than a regular ward
The study team makes the final eligibility decision.
Where it's taking place
- Stockholm, Sweden
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Stockholm, Sweden. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.