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New treatment option for Thyroid Diseases
Official title Dexmedetomidine for Improving Emergence Quality in Thyroid Surgery
ClinicalTrials.gov ID: NCT07462195
What this study is testing
What is Dexmedetomidine?
Dexmedetomidine is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for thyroid diseases.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Thyroid surgery requires smooth emergence from anesthesia to minimize coughing, hemodynamic fluctuations, and agitation during extubation, which may contribute to postoperative complications such as bleeding or cervical hematoma. Dexmedetomidine, a selective α2-adrenergic receptor agonist, has sedative, analgesic-sparing, and sympatholytic properties that may improve anesthetic stability and recovery quality.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- Age 18-65 years.
- American Society of Anesthesiologists (ASA) physical status I-III.
- Scheduled for elective thyroid surgery (thyroidectomy) under general anesthesia with endotracheal intubation.
- Able to understand the study procedures and provide written informed consent.
You likely can't join if
- Known hypersensitivity or contraindication to dexmedetomidine or study-related medications.
- Clinically significant cardiac conduction abnormality or arrhythmia (e.g., second- or third-degree atrioventricular block without a pacemaker)...
- Severe hepatic dysfunction or severe renal failure.
- Pregnancy or breastfeeding.
- Planned postoperative ICU admission or postoperative deterioration requiring ICU admission.
- Major intraoperative complications (e.g., major bleeding requiring urgent hemostatic intervention, tracheal or esophageal injury, or recurrent...
See the full eligibility criteria
- Age 18-65 years.
- American Society of Anesthesiologists (ASA) physical status I-III.
- Scheduled for elective thyroid surgery (thyroidectomy) under general anesthesia with endotracheal intubation.
- Able to understand the study procedures and provide written informed consent.
- Known hypersensitivity or contraindication to dexmedetomidine or study-related medications.
- Clinically significant cardiac conduction abnormality or arrhythmia (e.g., second- or third-degree atrioventricular block without a pacemaker), severe bradyarrhythmia, or unstable cardiovascular disease.
- Severe hepatic dysfunction or severe renal failure.
- Pregnancy or breastfeeding.
- Planned postoperative ICU admission or postoperative deterioration requiring ICU admission.
- Major intraoperative complications (e.g., major bleeding requiring urgent hemostatic intervention, tracheal or esophageal injury, or recurrent laryngeal nerve injury identified intraoperatively).
- Any condition that, in the investigator's judgment, would interfere with outcome assessment or increase risk (e.g., inability to reliably report pain scores or complete QoR-15).
The study team makes the final eligibility decision.
Where it's taking place
- Hanoi, Vietnam
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hanoi, Vietnam. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.