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New treatment option for Primary Open-Angle Glaucoma (POAG)
Official title Aqueous Humor and Ocular Tissue Analysis in Glaucoma and Cataract
ClinicalTrials.gov ID: NCT07462000
What this study is testing
- What it's testing
- This observational study will compare proteomic and elemental profiles of aqueous humor and ocular tissues in patients with primary open-angle glaucoma (POAG) and cataract versus cataract controls without glaucoma. Samples collected during standard surgery will be analyzed using LC-MS/MS and ICP-MS.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age ≥ 18 years.
- Scheduled for cataract surgery (phacoemulsification with intraocular lens implantation).
- Ability to provide written informed consent.
- For glaucoma arm: diagnosis of primary open-angle glaucoma (POAG) with coexisting cataract, and planned combined cataract surgery with glaucoma...
- For control arm: cataract without glaucoma and without other significant ocular pathology.
You likely can't join if
- Age \< 18 years.
- Pregnancy or breastfeeding.
- Advanced visual impairment in the study eye (visual aquity worse than counting fingers).
- Any glaucoma type other than primary open-angle glaucoma (e.g., angle-closure, secondary, neovascular glaucoma).
- History of intraocular surgery in the study eye (including glaucoma surgery), vitreoretinal surgery, corneal transplantation, or refractive surgery.
- Active or previous uveitis.
See the full eligibility criteria
- Age ≥ 18 years.
- Scheduled for cataract surgery (phacoemulsification with intraocular lens implantation).
- Ability to provide written informed consent.
- For glaucoma arm: diagnosis of primary open-angle glaucoma (POAG) with coexisting cataract, and planned combined cataract surgery with glaucoma procedure.
- For control arm: cataract without glaucoma and without other significant ocular pathology.
- Age \< 18 years.
- Pregnancy or breastfeeding.
- Advanced visual impairment in the study eye (visual aquity worse than counting fingers).
- Any glaucoma type other than primary open-angle glaucoma (e.g., angle-closure, secondary, neovascular glaucoma).
- History of intraocular surgery in the study eye (including glaucoma surgery), vitreoretinal surgery, corneal transplantation, or refractive surgery.
- Active or previous uveitis.
- Other significant chronic ocular disease in the study eye (other than cataract and POAG in the glaucoma arm).
- Inability to comply with study procedures or follow-up visits.
The study team makes the final eligibility decision.
Where it's taking place
- Warsaw, Poland
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Warsaw, Poland. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.