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New treatment option for Lung Resection Surgery
Official title Effect of Oxygen Administration in the Non-dependent Lung on Postoperative Complications After Lung Surgery
ClinicalTrials.gov ID: NCT07461779
What this study is testing
What is Medicinal gas - oxygen (Nippon Gases 200 bar)?
Medicinal gas - oxygen (Nippon Gases 200 bar) is an investigational medicine, being studied as a potential treatment for lung resection surgery.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The purpose of this study is to analyze the effectiveness of apneic oxygenation and CPAP applied to the non-dependent lung during pulmonary resection surgery in reducing inflammatory response, ischemia-reperfusion injury, and postoperative complications. We will conduct a randomized, controlled, and blinded study in 177 patients with three arms: Control Group: Oxygen therapy according to standard clinical practice Apneic oxygenation group: A probe will be introduced through the lumen of the double-lumen tube (DLT) to administer a continuous source of oxygen without any mechanism that generates airway pressure.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Patients of both genders undergoing lung resection surgery in the Thoracic Surgery Department at Hospital General Universitario Gregorio Marañón
- Lung isolation using a double-lumen tube (DLT)
- Scheduled surgery
- Patients able and willing to give written informed consent
- Patients over 18 years old and legally competent
You likely can't join if
- Patients with evidence of pulmonary bullae
- Pregnancy or breastfeeding
- Blood transfusion within 10 days prior to surgery
- Treatment with immunosuppressants or corticosteroids within 3 months prior to surgery
- Patient refusal to participate
- Prior contralateral thoracic surgery
See the full eligibility criteria
- Patients of both genders undergoing lung resection surgery in the Thoracic Surgery Department at Hospital General Universitario Gregorio Marañón
- Lung isolation using a double-lumen tube (DLT)
- Scheduled surgery
- Patients able and willing to give written informed consent
- Patients over 18 years old and legally competent
- Patients with evidence of pulmonary bullae
- Pregnancy or breastfeeding
- Blood transfusion within 10 days prior to surgery
- Treatment with immunosuppressants or corticosteroids within 3 months prior to surgery
- Patient refusal to participate
- Prior contralateral thoracic surgery
- Robotic surgery
- Pneumonectomy
- Enrollment in another clinical trial
The study team makes the final eligibility decision.
Where it's taking place
- Madrid, Spain
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Madrid, Spain. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.