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New treatment option for Pituitary Adenoma
Official title Use of [18F] Fluoroethyl-L-tyrosine PET/MRI for Identifying Small Functional Pituitary Adenomas
ClinicalTrials.gov ID: NCT07456878
What this study is testing
What is FET-PET/MRI?
FET-PET/MRI is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for pituitary adenoma.
Also referred to as Fluoroethyl-L-tyrosine.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The purpose of this research is to evaluate the diagnostic role and clinical efficacy of investigational FET-PET/MRI in detecting MRI-occult primary or residual/recurrent functional pituitary adenomas (PAs) and its influence on clinical and surgical decisions.
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 75
You may be able to join if
- Patients 18 to 75 years of age with biochemically proven CD, Acromegaly, or tumor hyperprolactinemia as per current Endocrinology guidelines.
- Clinical DCE-MRI protocol that is negative or equivocal for identifiable tumor.
- Patient willing to have surgery if lesion found, or already scheduled for surgery and lesion identification would be helpful.
- Able to provide informed consent and be capable of completing the imaging protocols.
- Female people of childbearing potential (women of childbearing potential [WOCBP]) must have a negative urine pregnancy test ≤48 hours prior to the...
You likely can't join if
- Patients with contraindications to MRI or PET scans.
- Patients with known allergies to contrast agents or other imaging-related materials.
- Patients with severe medical conditions that preclude participation in the study (e.g. inability to lie supine for 30-60 minutes).
- Patients with successful MRI localization of the adenoma.
The study team makes the final eligibility decision.
Where it's taking place
- Jacksonville, Florida, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 75 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Jacksonville, Florida, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.