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Tests treatment safety and results for Malocclusions
Official title Assessment of the Locally Administrated Vitamin D3 and Corticision Efficacy on Orthodontic Canine Retraction
ClinicalTrials.gov ID: NCT07455656
What this study is testing
What is patients will receive local application of vitamin D3 combined with corticision?
patients will receive local application of vitamin D3 combined with corticision is an investigational medicine, given as a monthly pill taken by mouth, being studied as a potential treatment for malocclusions.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- To study the effect vitamin D effect on orthodontic tooth movement when used in combination with coticision technique, independent t test or an equivalent non-parametric test will be used for comparison. According to a previous study by (S.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 13 to 20. Healthy volunteers may be eligible.
You may be able to join if
- Orthodontic patients referred for therapeutic extraction of bilateral maxillary first premolars (Angle Class II division 1 cases, with crowding and...
- Fully erupted permanent teeth (except third molar).
- Age 13-20 patients.
- No previous orthodontic treatment.
- Good oral and general health.
You likely can't join if
- Patients with impacted canines.
- Patients with severe crowding.
- Patients with untreated decay or any endodontic lesions.
- Patients with thyroid, parathyroid, or renal and liver disease.
See the full eligibility criteria
- Orthodontic patients referred for therapeutic extraction of bilateral maxillary first premolars (Angle Class II division 1 cases, with crowding and bimaxillary protrusion).
- Fully erupted permanent teeth (except third molar).
- Age 13-20 patients.
- No previous orthodontic treatment.
- Good oral and general health.
- No systemic disease or regular medication that could interfere with and/or affect orthodontic teeth movement.
- Patients with impacted canines.
- Patients with severe crowding.
- Patients with untreated decay or any endodontic lesions.
- Patients with thyroid, parathyroid, or renal and liver disease.
The study team makes the final eligibility decision.
Where it's taking place
- Cairo, Cairo Governorate, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 13 years to 20 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Cairo, Cairo Governorate, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.