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New treatment option for Plaque Psoriasis
Official title An Open-Label Extension Study of ORKA-001 in Participants With Plaque Psoriasis
ClinicalTrials.gov ID: NCT07449702
What this study is testing
What is ORKA-001?
ORKA-001 is an investigational medicine, given as an injection under the skin, being studied as a potential treatment for plaque psoriasis.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- An open-label extension (OLE) study to evaluate the long-term safety and efficacy of ORKA-001 in adult participants with moderate-to-severe plaque psoriasis, who previously participated in an Oruka Therapeutics sponsored study.
- Phase 2: a mid-size study of how well it works
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Signed informed consent by participants from previous trial choosing to transition into the OLE.
- Participants who have successfully completed the preceding trial.
- For women of childbearing potential, must have a negative urine pregnancy test at Baseline visit.
- For women of childbearing potential and fertile male participants with a partner of childbearing potential must be willing to continue to use highly...
You likely can't join if
- Participants who experienced any adverse events with ORKA-001 in the preceding trial that led to permanent investigational medicinal product...
- Participants who have developed guttate, erythrodermic or pustular psoriasis or drug-induced psoriasis (as diagnosed by the Investigator), during the...
- Evidence of current or previous clinically significant disease, medical condition other than psoriasis, or finding during the medical examination...
- Any clinically significant laboratory abnormality based on the last available lab results received during the preceding trial, that, according to the...
- Participant is pregnant or breastfeeding.
The study team makes the final eligibility decision.
Where it's taking place
- Fountain Valley, California, United States
- Los Angeles, California, United States
- San Diego, California, United States
- Santa Ana, California, United States
- Santa Monica, California, United States
- Cromwell, Connecticut, United States
- Miami, Florida, United States
- Rolling Meadows, Illinois, United States
- Bowling Green, Kentucky, United States
- Rockville, Maryland, United States
- Boston, Massachusetts, United States
- Detroit, Michigan, United States
- New York, New York, United States
- Portland, Oregon, United States
- Norfolk, Virginia, United States
- Edmonton, Alberta, Canada
- Surrey, British Columbia, Canada
- London, Ontario, Canada
- Markham, Ontario, Canada
- Peterborough, Ontario, Canada
+ 2 more site(s).
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Fountain Valley, California, United States; Los Angeles, California, United States; San Diego, California, United States; Santa Ana, California, United States; Santa Monica, California, United States; Cromwell, Connecticut, United States and 16 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.