BridgeMD
New treatment option for Apical Periodontitis
Official title Evaluation of Revitalization Success Using i-PRF in Non-Surgical Root Canal Retreatment
ClinicalTrials.gov ID: NCT07448571
What this study is testing
- What it's testing
- The goal of this randomized controlled clinical trial is to determine whether regenerative endodontic treatment can improve healing outcomes in teeth with apical periodontitis following failed root canal treatment. The study includes adult patients who require non-surgical root canal retreatment due to persistent periapical lesions.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 50
You may be able to join if
- Patients aged between 18 and 50 years.
- Single-rooted maxillary anterior teeth with closed apices.
- Presence of periapical lesion confirmed radiographically.
- Previously treated root canal tooth requiring non-surgical retreatment.
- Tooth has not previously undergone non-surgical root canal retreatment.
You likely can't join if
- Teeth without radiographic evidence of periapical lesion.
- Teeth with developmental anomalies.
- Patients with systemic diseases that may affect healing.
- Pregnant patients.
- Teeth presenting with internal or external root resorption.
See the full eligibility criteria
- Patients aged between 18 and 50 years.
- Single-rooted maxillary anterior teeth with closed apices.
- Presence of periapical lesion confirmed radiographically.
- Previously treated root canal tooth requiring non-surgical retreatment.
- Tooth has not previously undergone non-surgical root canal retreatment.
- Tooth is considered restorable.
- Patient is systemically healthy.
- Patient is willing to participate and provides informed consent.
- Teeth without radiographic evidence of periapical lesion.
- Teeth with developmental anomalies.
- Patients with systemic diseases that may affect healing.
- Pregnant patients.
- Teeth presenting with internal or external root resorption.
The study team makes the final eligibility decision.
Where it's taking place
- Istanbul, Turkey (Türkiye)
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 50 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Istanbul, Turkey (Türkiye). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.