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New treatment option for Sarcopenia
Official title Exercise During Hemodialysis: Impact on Sarcopenia and Sleep Quality
ClinicalTrials.gov ID: NCT07447375
What this study is testing
- What it's testing
- Sarcopenia (the loss of muscle mass, strength, and function) is highly prevalent in patients with Chronic Kidney Disease (CKD) undergoing hemodialysis, significantly increasing the risk of falls, frailty, and mortality. Despite its impact, there is a lack of evidence regarding the effectiveness of exercise programs specifically designed to address sarcopenia under the latest international diagnostic criteria (EWGSOP2) in older renal patients.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 40 and older
You may be able to join if
- people currently enrolled in a Chronic Hemodialysis Unit.
- Patients who have been on hemodialysis treatment for more than 3 months.
- people aged 40 years or older.
- Hemoglobin levels greater than 10 mg/dl.
- Ability to perform physical fitness assessment tests or dynamometry.
You likely can't join if
- Presence of intradialytic instability.
- Medical conditions where exercise is contraindicated: active infectious process, neoplasms, uncontrolled arrhythmias, or left ventricular dysfunction...
- Musculoskeletal or respiratory alterations that worsen with exercise.
- Lower limb amputation without a prosthesis.
- Cerebrovascular disease (stroke with sequelae or transient ischemic attacks within the previous 6 weeks).
- Uncontrolled hypertension (Systolic BP \> 200 mmHg or Diastolic BP \> 120 mmHg).
See the full eligibility criteria
- people currently enrolled in a Chronic Hemodialysis Unit.
- Patients who have been on hemodialysis treatment for more than 3 months.
- people aged 40 years or older.
- Hemoglobin levels greater than 10 mg/dl.
- Ability to perform physical fitness assessment tests or dynamometry.
- Willingness and ability to provide signed informed consent
- Presence of intradialytic instability.
- Medical conditions where exercise is contraindicated: active infectious process, neoplasms, uncontrolled arrhythmias, or left ventricular dysfunction (EF \< 35%).
- Musculoskeletal or respiratory alterations that worsen with exercise.
- Lower limb amputation without a prosthesis.
- Cerebrovascular disease (stroke with sequelae or transient ischemic attacks within the previous 6 weeks).
- Uncontrolled hypertension (Systolic BP \> 200 mmHg or Diastolic BP \> 120 mmHg).
- Unstable angina (at rest or during exercise) or history of coronary bypass/ischemic heart disease within the previous 6 weeks.
- Diabetes mellitus with severe decompensation (blood glucose \> 300 mg/dl).
- Dialysis-related hypotension (mean blood pressure \< 90/70 mmHg).
- Psychiatric or cognitive alterations that prevent collaboration with muscle training programs.
- Presence of an arteriovenous fistula in a lower limb.
- Motor neurological injury causing dysfunction that prevents the application of the strength protocol.
- Hospitalization within the 3 months prior to the study.
- Lack of cooperation (defined as failing to attend more than 25% of sessions) or inability to understand the treatment.
The study team makes the final eligibility decision.
Where it's taking place
- Salamanca, Salamanca, Spain
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 40 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Salamanca, Salamanca, Spain. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.