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New treatment option for Laparoscopic Cholecystectomy
Official title Low-Flow Sevoflurane and Desflurane Anesthesia in Laparoscopic Cholecystectomy
ClinicalTrials.gov ID: NCT07440758
What this study is testing
What is Sevoflurane?
Sevoflurane is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for laparoscopic cholecystectomy.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Several studies have demonstrated that inhalational anesthetic agents such as desflurane and sevoflurane may cause varying degrees of postoperative sore throat, hoarseness, and cough in orotracheally intubated patients. However, data evaluating these outcomes under low-flow anesthesia conditions remain limited and insufficient.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- American Society of Anesthesiologists (ASA) physical status I-II
- Aged between 18 and 65 years
- Patients who provide written informed consent to participate in the study
You likely can't join if
- Patients with a recent history of upper respiratory tract infection
- Patients with a recent history of sore throat
- Patients with chronic cough
- Patients with a history of previous neck or tracheal surgery
- Patients with predictors of difficult intubation
- Patients with a history of difficult intubation
See the full eligibility criteria
- American Society of Anesthesiologists (ASA) physical status I-II
- Aged between 18 and 65 years
- Patients who provide written informed consent to participate in the study
- Patients with a recent history of upper respiratory tract infection
- Patients with a recent history of sore throat
- Patients with chronic cough
- Patients with a history of previous neck or tracheal surgery
- Patients with predictors of difficult intubation
- Patients with a history of difficult intubation
- Obese patients (BMI \> 35 kg/m²)
- Patients with chronic respiratory diseases (asthma, COPD)
- Pregnancy
- Use of dexamethasone
- Patients with hepatic impairment
- Patients with allergy to paracetamol, tramadol, granisetron, dexamethasone, or metoclopramide
- Patients with known allergy to halogenated anesthetic agents
- Patients with a history of malignant hyperthermia
- Patients with mental disorders or those unable to provide reliable assessment
The study team makes the final eligibility decision.
Where it's taking place
- Kayseri, Kocasinan, Turkey (Türkiye)
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Kayseri, Kocasinan, Turkey (Türkiye). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.