BridgeMD
New treatment option for Cannabis
Official title Repeated CBD Administration and Cannabis Outcomes
ClinicalTrials.gov ID: NCT07434895
What this study is testing
What is Cannabidiol, Medium Dose?
Cannabidiol, Medium Dose is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for cannabis.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This outpatient study examines how cannabidiol (CBD) affects the behavioral and pain-relieving effects of cannabis.
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 55. Healthy volunteers may be eligible.
You may be able to join if
- English-speaking, literate adults,
- Male or female,
- Between the ages of 18-55,
- Body Mass Index from 18.5-32.0 kg/m2,
- Not currently seeking treatment for cannabis or drug use,
You likely can't join if
- Physiologic drug dependence on opioids, benzodiazepines, barbiturates, and/or alcohol that would require medical management,
- Clinically significant acute medical problem (e.g., infection) or chronic medical problem requiring daily medication or ongoing medical care (e.g...
- Current or past history of major psychiatric disorder that would limit ability to participate in the study,
- Use of cannabis exclusively for medical reasons (no recreational use reported),
- Current, unrelenting chronic pain that prevents participation (i.e., unable to sit in chair for 8 hours),
- Currently using daily prescription medications to manage medical conditions or any drug that could interfere with the study, including potent CYP2C9...
See the full eligibility criteria
- English-speaking, literate adults,
- Male or female,
- Between the ages of 18-55,
- Body Mass Index from 18.5-32.0 kg/m2,
- Not currently seeking treatment for cannabis or drug use,
- Able to provide written informed consent and perform all study procedures,
- If female, a negative pregnancy test and use of an effective form of contraception during study participation (e.g., oral contraceptive, abstinence, barrier method),
- Negative urine drug test for drugs of abuse (other than cannabis) prior to every Laboratory Session, and
- Otherwise healthy as determined by the investigator based on medical history, physical examination, vital signs, and laboratory chemistries.
- Physiologic drug dependence on opioids, benzodiazepines, barbiturates, and/or alcohol that would require medical management,
- Clinically significant acute medical problem (e.g., infection) or chronic medical problem requiring daily medication or ongoing medical care (e.g., hypertension, cardiovascular disease, diabetes, respiratory disorders...
- Current or past history of major psychiatric disorder that would limit ability to participate in the study,
- Use of cannabis exclusively for medical reasons (no recreational use reported),
- Current, unrelenting chronic pain that prevents participation (i.e., unable to sit in chair for 8 hours),
- Currently using daily prescription medications to manage medical conditions or any drug that could interfere with the study, including potent CYP2C9, CYP3A4, or CYP2C19 inducers,
- Clinically significant abnormal ECG (as determined by study physician/cardiologist),
- Clinically significant abnormal laboratory findings,
- History of seizure disorder,
- Clinically significant history of head injuries requiring medical management or long lasting sequalae, and
- Self-report of past 30-day use of synthetic cannabis (i.e., K2, Spice).
The study team makes the final eligibility decision.
Where it's taking place
- Lexington, Kentucky, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 55 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Lexington, Kentucky, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.