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Compares treatment options for Atelectasis, Postoperative
Official title Single-step vs Stepwise Lung Recruitment Maneuvers After Cardiopulmonary Bypass
ClinicalTrials.gov ID: NCT07432477
What this study is testing
- What it's testing
- This prospective randomized controlled trial aims to compare the hemodynamic and pulmonary effects of single-step and stepwise lung recruitment maneuvers in adult patients undergoing elective cardiac surgery with cardiopulmonary bypass. After separation from cardiopulmonary bypass, patients will be randomized to receive either a single-step sustained inflation recruitment maneuver or a stepwise incremental recruitment maneuver, both combined with 8 cmH₂O positive end-expiratory pressure.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- Age 18-80 years
- ASA (American Society of Anesthesiologists) II-IV
- Patients undergoing elective cardiac surgery (coronary artery bypass grafting, mitral valve replacement, aortic valve replacement)
You likely can't join if
- Emergency surgery
- Presence of perioperative arrhythmia
- \<35% left ventricular ejection fraction
- \>50 mmHg systolic pulmonary artery pressure
- Known chronic obstructive pulmonary disease or interstitial lung disease
- Pneumothorax
See the full eligibility criteria
- Age 18-80 years
- ASA (American Society of Anesthesiologists) II-IV
- Patients undergoing elective cardiac surgery (coronary artery bypass grafting, mitral valve replacement, aortic valve replacement)
- Emergency surgery
- Presence of perioperative arrhythmia
- \<35% left ventricular ejection fraction
- \>50 mmHg systolic pulmonary artery pressure
- Known chronic obstructive pulmonary disease or interstitial lung disease
- Pneumothorax
- Mean arterial pressure \<60 mmHg during recruitment maneuver
- New York Heart Association (NYHA) class III-IV heart failure
- Advanced cardiomyopathy or severe mitral regurgitation
- Cross-clamp time longer than 2 hours
- Requirement for high-dose inotropic or vasopressor support
- Patients who cannot be extubated after postoperative 24 hours
The study team makes the final eligibility decision.
Where it's taking place
- Samsun, Turkey (Türkiye)
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Samsun, Turkey (Türkiye). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.