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New treatment option for Atrial Fibrillation (AF)
Official title Exercise and Dietary Lifestyle Intervention on Reducing Atrial Fibrillation Burden, Cardiac and Body Fat Mass.
ClinicalTrials.gov ID: NCT07430007
What this study is testing
- What it's testing
- Atrial fibrillation (AF) is the most common cardiac arrhythmia and is strongly associated with obesity and excess body fat. Lifestyle interventions, including exercise and dietary modification, may reduce AF burden, but long-term randomized controlled trial evidence with objective AF burden assessment and advanced cardiac imaging is limited.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 75. Healthy volunteers may be eligible.
You may be able to join if
- Age 18-75 years
- Body mass index (BMI) ≥27 kg/m²
- Documented atrial fibrillation (paroxysmal or persistent)
- Ability to participate in exercise training and follow study procedures
- Access to a smartphone or device enabling rhythm monitoring
You likely can't join if
- Permanent atrial fibrillation
- Unstable angina pectoris or acute coronary syndrome within the past 3 months
- Participation in other lifestyle or drug weight reduction trials
- Significant left ventricular dysfunction (ejection fraction \<30%)
- Severe valvular heart disease or planned cardiac surgery
- Severe heart failure (NYHA class IV) or severe angina (CCS class IV)
See the full eligibility criteria
- Age 18-75 years
- Body mass index (BMI) ≥27 kg/m²
- Documented atrial fibrillation (paroxysmal or persistent)
- Ability to participate in exercise training and follow study procedures
- Access to a smartphone or device enabling rhythm monitoring
- Provides written informed consent
- Permanent atrial fibrillation
- Unstable angina pectoris or acute coronary syndrome within the past 3 months
- Participation in other lifestyle or drug weight reduction trials
- Significant left ventricular dysfunction (ejection fraction \<30%)
- Severe valvular heart disease or planned cardiac surgery
- Severe heart failure (NYHA class IV) or severe angina (CCS class IV)
- Unstable coronary artery disease or recent myocardial infarction
- Severe pulmonary disease limiting exercise capacity
- Active malignancy
- Autoimmune or systemic inflammatory diseases
- Severe renal or hepatic failure
- Memory disease or significant cognitive impairment
- Unstable psychiatric condition
- Recent joint or back surgery within the past 6 months
- Continuing back or joint pain symptoms and inability to take part in individualized exercise training
- Contraindications to exercise testing or training, including cardiac symptoms or cardiovascular symptoms, making exercise unsafe
- Pregnancy or breastfeeding
- Participation in another treatment study
- Any condition judged by investigators to make participation unsafe or infeasible
The study team makes the final eligibility decision.
Where it's taking place
- Jyväskylä, Central Finland, Finland
- Kuopio, Eastern Finland, Finland
- Kuopio, Northern Savonia, Finland
- Tampere, Finland
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 75 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Jyväskylä, Central Finland, Finland; Kuopio, Eastern Finland, Finland; Kuopio, Northern Savonia, Finland; Tampere, Finland. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.