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New treatment option for Elevated LDL-C and High Cholesterol
Official title A Study of STX-1150 in Participants With Elevated Low-Density Lipoprotein Cholesterol (LDL-C)
ClinicalTrials.gov ID: NCT07428473
What this study is testing
What is STX-1150?
STX-1150 is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for elevated ldl-c and high cholesterol.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- STX-1150 is an investigational therapy designed to lower LDL-C by silencing a gene called PCSK9 in the liver. STX-1150 does not edit or permanently change the gene.
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 70
You may be able to join if
- Elevated serum LDL-C with or without LDL-C lowering medication
- Willing and able to give informed consent before initiation of any study-related procedures and willing to comply with all required study procedures
You likely can't join if
- Patients with history of an ASCVD event \</= 6 months.
- Any uncontrolled or serious disease, or any medical or surgical condition that may interfere with participation
- Diagnosis of familial hypercholesterolemia
- Active or history of liver disease
- Previous treatment with PCSK9-inhibitor or other prior treatment within a specified timeframe
- Clinically significant abnormal laboratory values
The study team makes the final eligibility decision.
Where it's taking place
- Clayton, Victoria, Australia
- Christchurch, Christchurch, New Zealand
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 70 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Clayton, Victoria, Australia; Christchurch, Christchurch, New Zealand. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.