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Compares treatment options for Alveolar Bone Loss
Official title Comparison of Customized Allogenic Versus Autogenous Bone Block Graft for Alveolar Ridge Augmentation
ClinicalTrials.gov ID: NCT07419269
What this study is testing
- What it's testing
- The aim of this study is to determine whether jawbone augmentations using allogeneic and autogenous bone blocks lead to comparable three-dimensional clinical and radiological outcomes. In addition, the study seeks to investigate whether there are differences regarding safety, biocompatibility, complications, and PROMs.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- 1-4 missing teeth that need to be replaced with dental implants
- Bone ridge width insufficient for dental implant placement; \<5 mm of width as measured in a cone beam computed tomography at the ideal prosthetic...
- Medically healthy with no known allergies to antibiotics
- Non-smoker or light smoker (\< 10) or previous smoker who had quit for 5 years or more
- Periodontal health, as confirmed by clinical examination (Full mouth bleeding score and full mouth plaque score \< 25%) and at least one neighboring...
You likely can't join if
- All contraindications against implant treatment or augmentative procedures (e.g., advanced systemic diseases, corticosteroid medication...
- Treatments or diseases that may have an effect on bone turnover or the bone itself or non-mineralized tissue metabolism (e.g., bisphosphonates or...
- Pathological fractures such as those observed in (but not limited to) Paget's disease or in metastatic bone diseases
- Any active malignancy or patient undergoing treatment for a malignancy Study protocol: IndiALLO Version 4/19.03.2025 Page 9 von 32
- Contraindications to the class of drugs under study, e.g., known hypersensitivity or allergy to class of drugs or the investigational product
- Persistent compartment syndrome or neurovascular residua of compartment syndrome
See the full eligibility criteria
- 1-4 missing teeth that need to be replaced with dental implants
- Bone ridge width insufficient for dental implant placement; \<5 mm of width as measured in a cone beam computed tomography at the ideal prosthetic position
- Medically healthy with no known allergies to antibiotics
- Non-smoker or light smoker (\< 10) or previous smoker who had quit for 5 years or more
- Periodontal health, as confirmed by clinical examination (Full mouth bleeding score and full mouth plaque score \< 25%) and at least one neighboring natural tooth to the defect site(s)
- Age of 18 or above
- All contraindications against implant treatment or augmentative procedures (e.g., advanced systemic diseases, corticosteroid medication, immunodeficiency, pregnancy, intention to become pregnant, breastfeeding, lack of...
- Treatments or diseases that may have an effect on bone turnover or the bone itself or non-mineralized tissue metabolism (e.g., bisphosphonates or local radiotherapy, skeletal immaturity)
- Pathological fractures such as those observed in (but not limited to) Paget's disease or in metastatic bone diseases
- Any active malignancy or patient undergoing treatment for a malignancy Study protocol: IndiALLO Version 4/19.03.2025 Page 9 von 32
- Contraindications to the class of drugs under study, e.g., known hypersensitivity or allergy to class of drugs or the investigational product
- Persistent compartment syndrome or neurovascular residua of compartment syndrome
The study team makes the final eligibility decision.
Where it's taking place
- Graz, Styria, Austria
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Graz, Styria, Austria. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.