New treatment option for Pediatric Brain Tumors
Official title GenoDrugP 2025: Study on Three-dimensional Models Derived From Brain Tumors in Pediatric Patients
ClinicalTrials.gov ID: NCT07417072
What this study is testing
- What it's testing
- Central nervous system tumours are the most common solid tumours and the leading cause of cancer mortality in children, with high biological and prognostic heterogeneity. Despite advances in the 2021 WHO molecular classifications, treatment options remain limited and often ineffective in high-grade tumours.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 3 to 18
You may be able to join if
- Patients aged 3-18 years with suspected brain tumours undergoing neurosurgery
- No previous bone marrow transplants or other haematological procedures that could potentially interfere with germline analysis.
- Patients who have not received any systemic anticancer treatment (including chemotherapy, radiotherapy or targeted therapies) prior to enrolment...
- Signature of informed consent
You likely can't join if
- Subsequent histological confirmation of non-neoplastic brain pathology (e.g. malformations, inflammatory lesions, demyelinating processes).
- Insufficient quantity or quality of tumour tissue or peripheral blood for the analyses required by the protocol.
- Presence of serious clinical conditions, systemic infections or haemodynamic instability that contraindicate the collection of biological samples or...
The study team makes the final eligibility decision.
Where it's taking place
- Florence, Firenze, Italy
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 3 years to 18 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Florence, Firenze, Italy. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.