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New treatment option for Carotid Stenosis
Official title Remote Ischemic Conditioning Plus Stenting for Symptomatic Carotid Artery Stenosis
ClinicalTrials.gov ID: NCT07412249
What this study is testing
- What it's testing
- Remote ischemic conditioning (RIC) has emerged as a promising non-invasive strategy to protect the brain, with evidence suggesting its benefit in patients with carotid artery stenting (CAS). However, the long-term benefit and safety of chronic RIC in this population remain unknown.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 40 and older
You may be able to join if
- Age ≥ 40 years old;
- Patients with symptomatic moderate to severe stenosis of the internal carotid artery;
- History of ipsilateral cerebral ischemic symptoms within the past 180 days;
- Planned for carotid artery stent;
- Essen Score ≥ 3;
You likely can't join if
- Uncontrolled severe hypertension (systolic blood pressure \> 180 mmHg or diastolic blood pressure \> 110 mmHg despite medication)
- Subclavian artery stenosis ≥ 50% or presence of subclavian steal syndrome
- Severe hematological disorders or significant coagulation abnormalities
- Contraindications to remote ischemic conditioning, such as severe soft tissue injury, fracture, or vascular injury in the upper limbs, or peripheral...
- Severe comorbid conditions with a life expectancy of less than 1 year
- Participation in another clinical trial within the past 3 months or ongoing participation
See the full eligibility criteria
- Age ≥ 40 years old;
- Patients with symptomatic moderate to severe stenosis of the internal carotid artery;
- History of ipsilateral cerebral ischemic symptoms within the past 180 days;
- Planned for carotid artery stent;
- Essen Score ≥ 3;
- Modified Rankin Scale score of 0 or 1;
- Signed informed consent.
- Uncontrolled severe hypertension (systolic blood pressure \> 180 mmHg or diastolic blood pressure \> 110 mmHg despite medication)
- Subclavian artery stenosis ≥ 50% or presence of subclavian steal syndrome
- Severe hematological disorders or significant coagulation abnormalities
- Contraindications to remote ischemic conditioning, such as severe soft tissue injury, fracture, or vascular injury in the upper limbs, or peripheral vascular disease in the distal upper limbs
- Severe comorbid conditions with a life expectancy of less than 1 year
- Participation in another clinical trial within the past 3 months or ongoing participation
- Any other circumstances deemed by the investigator as unsuitable for participation in this clinical study.
The study team makes the final eligibility decision.
Where it's taking place
- Shenyang, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 40 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Shenyang, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.