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New treatment option for Ventilation Acquired Pneumonia
Official title Effect of Acetylcysteine Inhalation on Incidence and Time to Develop Ventilator Associated Pneumonia in Critically Ill Mechanically Ventilated Patients
ClinicalTrials.gov ID: NCT07409727
What this study is testing
What is Acetyl cysteine?
Acetyl cysteine is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for ventilation acquired pneumonia.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Background Mechanical ventilation is an essential medical intervention in the context of critical illness. However, the intervention is associated with a risk of significant, potentially preventable complications.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 64
You may be able to join if
- Aged 18-64 years, either male or female.
- Critically ill patients who have undergone intubation and are on mechanical ventilation.
- Expected duration of mechanical ventilation of more than 48 hours.
- Provided consent to participate in this clinical trial by next of kin.
You likely can't join if
- Patients currently on long-term NAC treatment.
- Confirmed brain death.
- Recent chest infection.
- Immunocompromised patients on immunosuppressive medication.
- Patients mechanically ventilated in another hospital.
- Pregnant women.
See the full eligibility criteria
- Aged 18-64 years, either male or female.
- Critically ill patients who have undergone intubation and are on mechanical ventilation.
- Expected duration of mechanical ventilation of more than 48 hours.
- Provided consent to participate in this clinical trial by next of kin.
- Patients currently on long-term NAC treatment.
- Confirmed brain death.
- Recent chest infection.
- Immunocompromised patients on immunosuppressive medication.
- Patients mechanically ventilated in another hospital.
- Pregnant women.
- Mean arterial pressure (MAP) \<60 mmHg despite adequate resuscitation and vasopressor therapy at the time of randomization.
- Known intolerance or hypersensitivity to study medication.
- Presence of a condition or abnormality that would compromise the quality of the data. \-
The study team makes the final eligibility decision.
Where it's taking place
- Cairo, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 64 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Cairo, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.