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New treatment option for Thoracic Neoplasms, Lung Diseases, Small Cell Lung Carcinoma
Official title A Study of YL201 in Combination With Other Anti-Cancer Therapies in Patients With Advanced Solid Tumors
ClinicalTrials.gov ID: NCT07407933
What this study is testing
What is YL201?
YL201 is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for thoracic neoplasms, lung diseases, small cell lung carcinoma.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This is a phase Ib/II, multicenter, open-label study of YL201 combined with atezolizumab. The study will include 2 parts.
- Phase 2: a mid-size study of how well it works
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- 1.18 years of age or older. 2. Histologically or cytologically confirmed diagnosis of ES-SCLC 3. Eastern Cooperative Oncology Group performance...
You likely can't join if
- No prior systemic anti-cancer treatment for ES-SCLC
- No prior treatment targeting B7H3 or topoisomerase I inhibitor
- No clinically active brain metastases or spinal cord compression
- No current or history of interstitial lung disease (ILD)/ pneumonitis
- No clinically significant cardiovascular disease (eg, New York Heart Association class II to IV congestive heart failure) Other protocol-defined...
The study team makes the final eligibility decision.
Where it's taking place
- Washington D.C., District of Columbia, United States
- Louisville, Kentucky, United States
- Houston, Texas, United States
- Fairfax, Virginia, United States
- Namur, Belgium
- Meldola, Italy
- Ravenna, Italy
- Otwock, Poland
- Poznan, Poland
- Przemyśl, Poland
- Craiova, Romania
- Badajoz, Spain
- Barcelona, Spain
- Madrid, Spain
- Manresa, Spain
- Valencia, Spain
- London, United Kingdom
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Washington D.C., District of Columbia, United States; Louisville, Kentucky, United States; Houston, Texas, United States; Fairfax, Virginia, United States; Namur, Belgium; Meldola, Italy and 11 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.