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New treatment option for Healthy Aging
Official title iVS-1 Probiotic Intervention Targeting Biological Aging in Midlife Adults
ClinicalTrials.gov ID: NCT07407894
What this study is testing
- What it's testing
- This study is a randomized, double-blind, placebo-controlled clinical trial designed to evaluate the effects of Bifidobacterium adolescentis (iVS-1) supplementation on biological aging markers, metabolic health, and functional health outcomes in midlife adults. The study explores whether modulation of aging-related biological pathways through the gut microbiome may influence health-related outcomes.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 40 to 75. Healthy volunteers may be eligible.
You may be able to join if
- Aged 40-75 years.
- BMI: 20-34.9 kg/m².
- Able and willing to sign informed consent and participate for the study duration.
You likely can't join if
- Chronic disease history (liver, kidney, heart).
- Current pregnancy and/or lactating.
- Colonoscopy and/or its preparation within 4 weeks of screening.
- Those who intend to have children during study period.
- Current probiotic, prebiotics and/or metabolic-altering supplement use.
- Those who are unable to cooperate with investigators and testing.
See the full eligibility criteria
- Aged 40-75 years.
- BMI: 20-34.9 kg/m².
- Able and willing to sign informed consent and participate for the study duration.
- Chronic disease history (liver, kidney, heart).
- Current pregnancy and/or lactating.
- Colonoscopy and/or its preparation within 4 weeks of screening.
- Those who intend to have children during study period.
- Current probiotic, prebiotics and/or metabolic-altering supplement use.
- Those who are unable to cooperate with investigators and testing.
- Known history of cancer and/or ongoing cancer treatments.
- Abuse of drugs, alcohol, tobacco, nicotine and other substances.
- History of cardiac diseases: atherosclerosis, heart failure, unstable angina, stable angina, etc., and chronic hypoxic disease: emphysema, pulmonary heart disease and others related.
- History of chronic and major GI disease (pancreatitis, IBS, and IBD) and intestinal surgeries.
- Type 1 or 2 diabetes mellitus.
- Poorly controlled chronic diseases (hypertension, hyperlipidemia) that are clinically unstable.
- Vulnerable groups, including clinically ill, mentally ill, cognitively impaired, minors, and illiterate etc.
- Significant weight loss (\>20%) in prior one month.
- Conditions affecting safety or outcome integrity.
The study team makes the final eligibility decision.
Where it's taking place
- New Port Richey, Florida, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 40 years to 75 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include New Port Richey, Florida, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.