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New treatment option for Pancreatitis, Acute Necrotizing
Official title Strategic Timing of Endoscopic Interventions in Infected Necrotizing Pancreatitis
ClinicalTrials.gov ID: NCT07406698
What this study is testing
- What it's testing
- Pancreatic necrosis complicates approximately 20-30% of severe acute pancreatitis cases. While many collections resolve without intervention, persistent symptomatic collections-particularly when infected-are associated with significant morbidity and mortality and frequently require procedural management.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age ≥ 18 years
- Patients with symptomatic necrotic collection diagnosed on MRI or CT abdomen/pelvis, defined as fluid collection in the setting of documented...
- Documented or suspected infected necrotizing pancreatitis 1) Documented infected necrotizing pancreatitis, defined as: i. Positive culture obtained...
- Temperature \>100.4 °F or \<96.8 °F
- Heart rate \> 90 beats/min
You likely can't join if
- Age \< 18 years
- \> 26 days after the onset of acute pancreatitis
- Indication for emergency laparotomy for abdominal catastrophe (e.g. bleeding, bowel perforation, abdominal compartment syndrome).
- Necrotic collection is not amenable for endoscopic intervention.
- Pregnancy.
- Unable to obtain informed consent from the patient or legally authorized representative.
See the full eligibility criteria
- Age ≥ 18 years
- Patients with symptomatic necrotic collection diagnosed on MRI or CT abdomen/pelvis, defined as fluid collection in the setting of documented pancreatic necrosis that contains necrotic material and encased within a...
- Documented or suspected infected necrotizing pancreatitis 1) Documented infected necrotizing pancreatitis, defined as: i. Positive culture obtained with percutaneous fine needle aspiration from the pancreatic necrotic...
- Temperature \>100.4 °F or \<96.8 °F
- Heart rate \> 90 beats/min
- Respiratory rate \>20 breaths/min or PaCO2 \< 32 mmHg
- WBC count \>12,000/mm³, or \<4,000/mm³, or more than 10% immature band cells
- CRP ≥ 30mg/L
- Procalcitonin ≥ 1ng/mL
- Endoscopic drainage of the necrotic collection is technically feasible as deemed by the treating physician.
- Age \< 18 years
- \> 26 days after the onset of acute pancreatitis
- Indication for emergency laparotomy for abdominal catastrophe (e.g. bleeding, bowel perforation, abdominal compartment syndrome).
- Necrotic collection is not amenable for endoscopic intervention.
- Pregnancy.
- Unable to obtain informed consent from the patient or legally authorized representative.
The study team makes the final eligibility decision.
Where it's taking place
- Orlando, Florida, United States
Compensation & support
A stipend or compensation may be offered.
Compensation likely.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Orlando, Florida, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.