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New treatment option for Idiopathic Infertility
Official title Biological Aging Hallmarks-Guided Integrative TCM and Conventional Medicine in Post-Treatment Unexplained Female Infertility
ClinicalTrials.gov ID: NCT07404969
What this study is testing
- What it's testing
- The goal of this clinical trial is to determine whether telomere profiling and other biological aging hallmarks can help identify underlying mechanisms of persistent infertility in women with post-treatment unexplained infertility. The study also evaluates whether a personalized integrative treatment guided by these biomarkers can improve reproductive outcomes.
- This is a blinded study.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 25 to 42, women only
You may be able to join if
- Biological female participants aged 25 to 42 years.
- Diagnosis of infertility defined as failure to conceive after at least 12 months of unprotected intercourse and/or repeated failure of assisted...
- History of post-treatment unexplained or functionally idiopathic infertility, defined as persistent infertility despite adequate correction or...
- Eligibility for natural conception attempts and/or assisted reproductive technologies according to routine clinical practice.
- Willingness to undergo biological aging biomarker profiling, including leukocyte telomere analysis.
You likely can't join if
- Current pregnancy or breastfeeding at the time of enrollment.
- Known chromosomal abnormalities or genetic conditions directly impairing fertility (e.g., Turner syndrome).
- Untreated severe male factor infertility precluding conception by natural or standard ART methods.
- Active malignancy or history of cancer requiring systemic treatment within the past 5 years.
- Severe systemic disease or medical condition contraindicating pregnancy or participation in ART (as determined by the treating physician).
- Use of investigational drugs or participation in another treatment clinical trial that could interfere with the study outcomes.
See the full eligibility criteria
- Biological female participants aged 25 to 42 years.
- Diagnosis of infertility defined as failure to conceive after at least 12 months of unprotected intercourse and/or repeated failure of assisted reproductive technologies (ART), including intrauterine insemination (IUI)...
- History of post-treatment unexplained or functionally idiopathic infertility, defined as persistent infertility despite adequate correction or management of identifiable reproductive conditions (e.g., endometriosis...
- Eligibility for natural conception attempts and/or assisted reproductive technologies according to routine clinical practice.
- Willingness to undergo biological aging biomarker profiling, including leukocyte telomere analysis.
- Ability and willingness to comply with study procedures, including the preconception integrative intervention and follow-up assessments.
- Provision of written informed consent prior to participation.
- Current pregnancy or breastfeeding at the time of enrollment.
- Known chromosomal abnormalities or genetic conditions directly impairing fertility (e.g., Turner syndrome).
- Untreated severe male factor infertility precluding conception by natural or standard ART methods.
- Active malignancy or history of cancer requiring systemic treatment within the past 5 years.
- Severe systemic disease or medical condition contraindicating pregnancy or participation in ART (as determined by the treating physician).
- Use of investigational drugs or participation in another treatment clinical trial that could interfere with the study outcomes.
- Known hypersensitivity or contraindication to components of the integrative intervention, as determined by clinical assessment.
- Any condition which, in the opinion of the investigator, would interfere with safe participation or interpretation of study results.
The study team makes the final eligibility decision.
Where it's taking place
- Neuchâtel, Switzerland
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 25 years to 42 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Neuchâtel, Switzerland. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.