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New treatment option for Large Vessel Occlusion
Official title Non-invasive Vagus Nerve Stimulation to Reduce Inflammation and Brain Injury Blood Biomarkers Following an Acute Ischemic Stroke
ClinicalTrials.gov ID: NCT07404852
What this study is testing
- What it's testing
- This is a randomized open-label, with blinded outcome pilot study to evaluate the effect on inflammatory and brain injury laboratory values and explore clinical outcomes in patients who present with ischemic strokes due to large vessel occlusions and are treated with either current accepted management, or accepted management in addition to transcutaneous auricular vagal nerve stimulation.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 99
You may be able to join if
- Adult patients who present with acute ischemic strokes due to large vessel occlusions
You likely can't join if
- \<18 years old
- patients with presumed chronic large vessel occlusions
- NIHSS\<6
- pre-morbid modified Rankin score (mRS) \>2
- unable to initiate treatment under 24 hours from symptom discovery
- Chronic or acute infection, Recent surgery, active immune disease
See the full eligibility criteria
- Adult patients who present with acute ischemic strokes due to large vessel occlusions
- \<18 years old
- patients with presumed chronic large vessel occlusions
- NIHSS\<6
- pre-morbid modified Rankin score (mRS) \>2
- unable to initiate treatment under 24 hours from symptom discovery
- Chronic or acute infection, Recent surgery, active immune disease
- life expectancy \<3 months
- patients' undergoing active cancer or immunosuppressive/modulating therapy
- patients with sustained bradycardia on arrival with a heart rate \<50 beats per minute.
The study team makes the final eligibility decision.
Where it's taking place
- St Louis, Missouri, United States
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 99 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include St Louis, Missouri, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.