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New treatment option for Acute Asthma
Official title Dosing of Steroids for Acute Asthma Given in the Emergency Department - a Pilot Randomised Feasibility Trial of Dexamethasone in Children
ClinicalTrials.gov ID: NCT07402707
What this study is testing
What is dexamethasone oral?
dexamethasone oral is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for acute asthma.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Steroids given by mouth are an important first line treatment for children presenting with asthma attacks. Dexamethasone is the steroid used in some emergency departments (EDs) because of the need for a single dose and as it is well tolerated.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 4 to 15
You may be able to join if
- Children aged 4-15 years (inclusive) presenting to the ED with an asthma exacerbation, where oral steroids are recommended by Trust/National...
- Children whose parents/carers do not speak English will also be eligible provided they speak one of the common languages where an interpreter and...
You likely can't join if
- Children who have been treated with oral or IV steroids in the last 2 weeks.
- Hypersensitivity to the study drug.
- Children who have concomitant stridor.
- First episode of wheezing (not previously diagnosed as asthma).
- Children with known difficult asthma who receive longer courses of steroids as standard.
- Life threatening episode of asthma.
See the full eligibility criteria
- Children aged 4-15 years (inclusive) presenting to the ED with an asthma exacerbation, where oral steroids are recommended by Trust/National guidelines.
- Children whose parents/carers do not speak English will also be eligible provided they speak one of the common languages where an interpreter and Information Sheets are available (Slovakian, Arabic and Urdu).
- Children who have been treated with oral or IV steroids in the last 2 weeks.
- Hypersensitivity to the study drug.
- Children who have concomitant stridor.
- First episode of wheezing (not previously diagnosed as asthma).
- Children with known difficult asthma who receive longer courses of steroids as standard.
- Life threatening episode of asthma.
- Children with other conditions that require them to have steroids when unwell.
- Children who are involved in current research or have recently been involved in research prior to recruitment
The study team makes the final eligibility decision.
Where it's taking place
- Sheffield, United Kingdom
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 4 years to 15 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Sheffield, United Kingdom. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.