BridgeMD
New treatment option for Post Endodontic Pain
Official title The Effects of Preemptive Multimodal Analgesic on Endodontic Pain Following Root Canal Therapy.
ClinicalTrials.gov ID: NCT07400471
What this study is testing
What is Pregabalin- Acetaminophen?
Pregabalin- Acetaminophen is an investigational medicine, being studied as a potential treatment for post endodontic pain.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- A clinical trial comparing preemptive multimodal analgesics with placebo in the management of immediate and chronic post-endodontic pain. The study utilizes statistical methods such as chi-squared, T-tests, and regression analysis, accounting for multiple outcomes with the Bonferroni adjustment.
- Phase 1: an early, usually small safety study
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older. Healthy volunteers may be eligible.
You may be able to join if
- Patient's aged 18 years more.
- ASA physical status I-II.
- Patient with the complain of pain originated from teeth and surrounding structure.
- Preoperative pain severity is moderate to severe.
- Patient can be able to make communication about their pain.
You likely can't join if
- Patient would not like to attain in research.
- Patients have any medical condition those are contra indication for study drug.
- ASA physical status III, IV, V.
- Patient already under treated any anti convulsent drug.
- Patient participant in other clinical trials.
- Lack of motivation or poor adharence to study protocols.
See the full eligibility criteria
- Patient's aged 18 years more.
- ASA physical status I-II.
- Patient with the complain of pain originated from teeth and surrounding structure.
- Preoperative pain severity is moderate to severe.
- Patient can be able to make communication about their pain.
- Patients give consent to attain this research.
- Patients have others concomitant chronic pain.
- Patients who will have non-surgical endodontic treatment.
- Patients who will have non-surgical endodontic retreatment.
- Patients who will have surgical endodontic treatment.
- Patient would not like to attain in research.
- Patients have any medical condition those are contra indication for study drug.
- ASA physical status III, IV, V.
- Patient already under treated any anti convulsent drug.
- Patient participant in other clinical trials.
- Lack of motivation or poor adharence to study protocols.
- Patient with Pregnancy
- Severe organ dysfunction
- Patient have Hepatitis B, and other cross infection disease like (HIV)
- Uncontrolled comorbidities that patient do not fit for endodontic treatment.
- Severe cognitive impaired patients.
- History of certain cancers or severe hematological issues.
The study team makes the final eligibility decision.
Where it's taking place
- Chittagong, Chattogram, Bangladesh
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Chittagong, Chattogram, Bangladesh. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.