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New treatment option for Bacterial Keratitis
Official title Intrastromal Moxifloxacin as an Adjunctive Therapy in Recalcitrant Bacterial Keratitis
ClinicalTrials.gov ID: NCT07394257
What this study is testing
What is Intrastromal moxifloxacin injection plus standard topical moxifloxacin therapy?
Intrastromal moxifloxacin injection plus standard topical moxifloxacin therapy is an investigational medicine, given as a treatment applied to the skin, being studied as a potential treatment for bacterial keratitis.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Bacterial keratitis is a potentially sight-threatening corneal infection that is commonly treated with intensive topical antibiotics. Despite appropriate therapy, some cases show inadequate clinical response, particularly when the infection involves the deep corneal stroma.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 20 and older
You may be able to join if
- Age ≥ 18 years
- Clinical diagnosis of bacterial keratitis confirmed by corneal scraping and microbiology
- Recalcitrant keratitis defined as no significant clinical improvement after 48-72 hours of intensive topical antibiotic therapy
- Ability to provide written informed consent
You likely can't join if
- Fungal, viral, or acanthamoeba keratitis
- Corneal perforation or impending perforation
- Known hypersensitivity to fluoroquinolones
- Pregnancy or lactation
- Immunocompromised state or current systemic immunosuppressive therapy
- Previous intrastromal or intracameral antibiotic injection for the same episode
The study team makes the final eligibility decision.
Where it's taking place
- Minya, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 20 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Minya, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.