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New treatment option for Children With Cerebral Palsy
Official title Remote Ischemic Conditioning and Spinal Reflex Modulation in Children With Cerebral Palsy
ClinicalTrials.gov ID: NCT07390760
What this study is testing
- What it's testing
- Remote ischemic conditioning (RIC) is a clinically feasible intervention involving brief, sublethal periods of ischemia followed by reperfusion that has been shown to enhance motor performance, strength, and balance when combined with training in healthy adults and individuals with neurological conditions. Although RIC is thought to influence neuroplasticity through neural, metabolic, and humoral pathways, its effects on spinal-level mechanisms remain poorly understood.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 8 to 17
You may be able to join if
- Children diagnosed with cerebral palsy (CP) between the ages 8-17 years
- Gross motor function classification system levels I-III
- Mainstream in school and has sufficient cognition to follow the experiment instructions
You likely can't join if
- Children with other developmental disabilities such as autism and developmental coordination disorders
- Children with cognitive deficits such as inability to understand and follow commands, substantially lower performance at grade level in school...
- Children with balance disorders such as vestibular disorders, posterior fossa tumor etc.
- Children with known cardiorespiratory dysfunctions
- Children with sickle cell disease
- Children who are receiving other adjunct therapies such as transcranial magnetic stimulation, transcranial direct current stimulation, or vagal nerve...
See the full eligibility criteria
- Children diagnosed with cerebral palsy (CP) between the ages 8-17 years
- Gross motor function classification system levels I-III
- Mainstream in school and has sufficient cognition to follow the experiment instructions
- Children with other developmental disabilities such as autism and developmental coordination disorders
- Children with cognitive deficits such as inability to understand and follow commands, substantially lower performance at grade level in school, and/or communication problems
- Children with balance disorders such as vestibular disorders, posterior fossa tumor etc.
- Children with known cardiorespiratory dysfunctions
- Children with sickle cell disease
- Children who are receiving other adjunct therapies such as transcranial magnetic stimulation, transcranial direct current stimulation, or vagal nerve stimulation
- Presence of lower extremity condition, injury, or surgery within last three months which could compromise conditioning and training.
- Participants who are pregnant.
The study team makes the final eligibility decision.
Where it's taking place
- Greenville, North Carolina, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 8 years to 17 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Greenville, North Carolina, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.