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Compares treatment options for Opioid Free Anesthesia
Official title Opioid-Free Anesthesia Versus Opioid Based Anesthesia For Adolescent Idiopathic Scoliosis
ClinicalTrials.gov ID: NCT07389096
What this study is testing
What is Dexmedetomidine?
Dexmedetomidine is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for opioid free anesthesia.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Opioid-free anesthesia (OFA) is a multimodal analgesic approach designed to eliminate the intraoperative use of systemic, neuraxial, or intracavitary opioids. This technique employs a combination of antinociceptive agents targeting various pathways within the central and peripheral nervous systems to achieve effective analgesia.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 8 to 18
You may be able to join if
- Patients younger than 18 years of age, classified as American Society of Anesthesiologists (ASA) Physical Status I or II, and will be scheduled for...
You likely can't join if
- Refusal to participate in the study or to allow use of personal data
- Non-idiopathic scoliosis
- Contraindications to commonly used perioperative medications
- ASA Physical Status ≥ III
- Presence of neuromuscular disorders or severe cardiac dysfunction
- Requirement for postoperative mechanical ventilation
See the full eligibility criteria
- Patients younger than 18 years of age, classified as American Society of Anesthesiologists (ASA) Physical Status I or II, and will be scheduled for surgical correction of adolescent idiopathic scoliosis.
- Refusal to participate in the study or to allow use of personal data
- Non-idiopathic scoliosis
- Contraindications to commonly used perioperative medications
- ASA Physical Status ≥ III
- Presence of neuromuscular disorders or severe cardiac dysfunction
- Requirement for postoperative mechanical ventilation
- Regular use of analgesics or opioids
- History of allergy to opioids or dexmedetomidine
- Diagnosed mental disorders
- Severe hepatic or renal dysfunction
- Coagulopathy or significant pulmonary disease
- Preoperative or postoperative neurological deficits
- Occurrence of serious arrhythmia, hypotension, or bradycardia necessitating discontinuation of dexmedetomidine infusion
The study team makes the final eligibility decision.
Where it's taking place
- Port Said, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 8 years to 18 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Port Said, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.