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New treatment option for Malaria Asymptomatic Parasitaemia
Official title Assessing the Feasibility of Combining Dihydroartemisinin Piperaquine and Primaquine for Malaria Mass Drug Administration in High Endemic Communities in the Eastern Region of Ghana
ClinicalTrials.gov ID: NCT07389057
What this study is testing
What is DHAP?
DHAP is an investigational medicine, given as an once-daily pill taken by mouth, being studied as a potential treatment for malaria asymptomatic parasitaemia.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Previous malaria control studies in Ghana have shown that community-wide approaches can substantially reduce malaria infections. In a mass testing, treatment and tracking (MTTT) study, more than 75% of people in target communities were reached, leading to a 24% reduction in asymptomatic malaria after one year.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 3 and older. Healthy volunteers may be eligible.
You may be able to join if
- must be aged 3 months and above and
- be resident in the communities for the period of the study,
- completed and signed a consent form from the parent or guardian of children below 18 years
- Completed and signed assent for 12-17 years old children.
- Completed and signed consent for those from age 18 years and above.
You likely can't join if
- Pregnant women
- individual with a life-threatening illness (excluding malaria)
- less than 10Kg body weight (or less than 1 year old)
- individuals who had experienced adverse effects related to primaquine or
- known to be G6PD deficient .
The study team makes the final eligibility decision.
Where it's taking place
- Accra, Eastern Region, Ghana
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 3 months and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Accra, Eastern Region, Ghana. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.