BridgeMD
New treatment option for Chronic Apical Periodontitis
Official title In Vivo Study on the Material Properties of iRoot SP and nRoot SP Root Canal Sealers
ClinicalTrials.gov ID: NCT07388901
What this study is testing
- What it's testing
- A randomized controlled trial was conducted to compare the treatment efficacy of iRoot SP and nRoot SP Root Canal Sealer Materials in patients with chronic apical periodontitis.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age ≥ 18 years.
- Diagnosis of apical periodontitis conforming to the diagnostic criteria in Endodontics.
- The affected tooth is deemed restorable upon evaluation, with non-vital pulp requiring extirpation.
- The affected tooth is a single tooth with a fully developed apical foramen.
- No root resorption and no significant morphological variation of the root canal.
You likely can't join if
- Patients with alveolar bone loss exceeding one-third of the root length.
- Affected teeth with root fracture, root canal obstruction, calcification, or root surface caries.
- Patients with severe systemic diseases (e.g., osteoporosis, mental disorders, hepatic or renal insufficiency).
- Patients who have taken analgesics, immunosuppressants, or antibiotics within one week prior to enrollment.
- Patients with concurrent periapical cysts, oral tumors, or other oral diseases.
- Pregnant or lactating patients.
See the full eligibility criteria
- Age ≥ 18 years.
- Diagnosis of apical periodontitis conforming to the diagnostic criteria in Endodontics.
- The affected tooth is deemed restorable upon evaluation, with non-vital pulp requiring extirpation.
- The affected tooth is a single tooth with a fully developed apical foramen.
- No root resorption and no significant morphological variation of the root canal.
- The affected tooth is undergoing primary root canal treatment.
- Periapical radiolucency with a diameter of 1-5 mm and no peripheral sclerotic border observed on preoperative radiographs.
- Patient is in normal mental state, conscious, and capable of normal communication.
- Patient has provided informed consent.
- Patients with alveolar bone loss exceeding one-third of the root length.
- Affected teeth with root fracture, root canal obstruction, calcification, or root surface caries.
- Patients with severe systemic diseases (e.g., osteoporosis, mental disorders, hepatic or renal insufficiency).
- Patients who have taken analgesics, immunosuppressants, or antibiotics within one week prior to enrollment.
- Patients with concurrent periapical cysts, oral tumors, or other oral diseases.
- Pregnant or lactating patients.
- Patients with dental phobia, severe gag reflex, limited mouth opening, or poor compliance.
- Patients with a known allergy to the root canal sealer materials.
The study team makes the final eligibility decision.
Where it's taking place
- Hangzhou, Zhejiang, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hangzhou, Zhejiang, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.