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New treatment option for Cardiac Arrest (CA)
Official title Diagnostic Accuracy of ECG-less Gated Cardiac CT in Resuscitated Cardiac Arrest Survivors Without ST Elevation Myocardial Infarction
ClinicalTrials.gov ID: NCT07388342
What this study is testing
- What it's testing
- In a significant portion of patients surviving a cardiac arrest, the event is caused by a myocardial infarction (a narrowing or blockage of one or more blood vessels that supply blood to the heart, the coronary arteries). In some people, this is immediately evident from basic tests; in others, it is more difficult to predict with the currently available tests whether this (or something else) caused the cardiac arrest.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Inclusion:
- Adults (≥18 years) with sustained return of spontaneous circulation (ROSC) following in/out-of-hospital cardiac arrest.
- Informed consent from patient or representative obtained before invasive coronary angiography.
- Exclusion
- Patients on VA-ECMO
See the full eligibility criteria
- Inclusion:
- Adults (≥18 years) with sustained return of spontaneous circulation (ROSC) following in/out-of-hospital cardiac arrest.
- Informed consent from patient or representative obtained before invasive coronary angiography.
- Exclusion
- Patients on VA-ECMO
- ACS STEMI or STEMI "equivalent"
- New left/right bundle branch block
- ST segment depression in leads V1-V3, when the terminal T wave is positive and concomitant ST-segment elevation ≥ 0,5mm recorded in leads V7-V9 (posterior MI)
- ST-segment elevation in V7-V9 (posterior MI) or V3R-V4R (RV MI)
- ACS NSTEMI with persistent ST depression despite optimal therapy, suggesting ongoing myocardial ischemia, with indication for an urgent ICA according to the treating physician.
- Hemodynamic/electrical instability precluding CT imaging (as perceived by the treating physician)
- Life-threatening arrhythmia potentially caused by acute myocardial ischemia
- Absolute contraindications to iodinated contrast
- Patients with a known non-cardiac cause of cardiac arrest (e.g., traumatic brain injury, overt hemorrhage, asphyxia/severe hypoxia due to known lung disease, trauma, severe metabolic/electrolyte derangement, or...
- Known or likely pregnancy or lactation
- Severe bleeding issue (as perceived by the treating physician) precluding heparin administration during radial access coronary angiography.
- Prior coronary intervention (stent implantation/CABG).
- CT findings indicating a condition that precludes coronary angiography in the short term.
- Patients with end-of-life care pathways.
- Participation in another intervention study interfering with the research questions in OPEN CCT Arrest.
The study team makes the final eligibility decision.
Where it's taking place
- Brussels, Vlaams Brabant, Belgium
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Brussels, Vlaams Brabant, Belgium. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.