BridgeMD
New treatment option for Mild Autonomous Cortisol Secretion Adenoma
Official title Ultradian Steroid Rhythms in Adrenal Incidentalomas
ClinicalTrials.gov ID: NCT07387419
What this study is testing
- What it's testing
- Twenty to 40% of adrenal incidentalomas are responsible for MACS (mild autonomous cortisol producing secretion). The biological tools used in current practice to explore MACS do not provide precise information on cortisol production abnormalities.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- 18 \< Age ≤ 85 years.
- Patient with one or more uni or bilateral adrenal nodules of cortical appearance on CT scan.
- Subject affiliated or beneficiary of a social security scheme. The diagnostic criteria are: For the MACS group:
- a serum cortisol concentration after a minute braking test with dexamethasone \> 50 nmol/L or 1.8 µg/dL, with a concomitant dexamethasone...
- morning plasma ACTH concentration ≤ 2.5 pmol/L or 11 pg/mL. For the non-secreting adenoma group: \- Plasma cortisol after minute dexamethasone...
You likely can't join if
- Age \< 18 years
- Pregnant or breast-feeding
- Use of oral estrogens (must be discontinued for at least 6 weeks prior to sampling)
- Known adrenal insufficiency and/or treatment with steroids (oral, inhaled, parenteral or topical) or other interfering drugs.
- patient taking part in another study
- Patients placed under legal protection measures and/or deprived of their liberty
The study team makes the final eligibility decision.
Where it's taking place
- Pessac, France
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Pessac, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.