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New treatment option for Obesity (Disorder)
Official title Tirzepatide and Muscle Outcomes in Obesity
ClinicalTrials.gov ID: NCT07373834
What this study is testing
What is Tirzepatide?
Tirzepatide is an investigational medicine, given as an once-weekly injection under the skin, being studied as a potential treatment for obesity (disorder).
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is evaluating whether a dual glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist, tirzepatide, can affect the function, structure and metabolism of skeletal muscles in adults with obesity. Participants, premenopausal females with obesity, will receive either tirzepatide or placebo over 24 weeks.
- Time commitment: about 24 weeks
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 50, women only
You may be able to join if
- Female sex
- Age between 18 and 50 years
- BMI between 30 kg/m² and 40 kg/m²
- Stable body weight within the three months preceding study enrolment (defined as ≤ 5% change)
- No prior pharmacological or surgical interventions for obesity treatment
You likely can't join if
- Sarcopenic obesity
- Pregnancy or lactation
- Postmenopausal status
- Diabetes
- Immobility
- Personal history of malignancy
See the full eligibility criteria
- Female sex
- Age between 18 and 50 years
- BMI between 30 kg/m² and 40 kg/m²
- Stable body weight within the three months preceding study enrolment (defined as ≤ 5% change)
- No prior pharmacological or surgical interventions for obesity treatment
- Commitment to use barrier contraception and absence of plans for pregnancy within 8 months following enrolment
- Sarcopenic obesity
- Pregnancy or lactation
- Postmenopausal status
- Diabetes
- Immobility
- Personal history of malignancy
- Personal history of pancreatitis
- Personal history of major depressive episodes
- Personal history of myopathy
- Personal or family history of medullary thyroid carcinoma
- Current treatment with metformin or systemic corticosteroids
The study team makes the final eligibility decision.
Where it's taking place
- Ljubljana, Slovenia
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 24 weeks per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling female, 18 years to 50 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Ljubljana, Slovenia. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.