BridgeMD
Compares treatment options for Non-Small Cell Lung Cancer (NSCLC)
Official title A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)
ClinicalTrials.gov ID: NCT07361510
What this study is testing
What is Pumitamig?
Pumitamig is an investigational medicine, being studied as a potential treatment for non-small cell lung cancer (nsclc).
Also referred to as BMS-986545.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The purpose of this study is to evaluate the efficacy of Pumitamig versus Pembrolizumab in participants with previously untreated advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%.
- Phase 3: a large, late-stage study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Participants must have a histologically or cytologically confirmed diagnosis of Non-Small Cell Lung Cancer (NSCLC) (squamous and nonsquamous) with...
- Participants must have a programmed death ligand-1 (PD-L1) expression ≥ 50%.
- Participants must have measurable disease as defined by Response Evaluation Criteria in Solid Tumors (RECIST) v1.1.
- Participants must have no prior systemic anti-tumor therapy for locally advanced or metastatic NSCLC.
- Participants must have an Eastern Cooperative Oncology Group (ECOG) Performance Status 0-1.
You likely can't join if
- Participants must not have any documented actionable genomic alteration (AGA) for which first-line (1L) approved therapies are indicated.
- Participants must not have any symptomatic untreated central nervous system (CNS) metastases, leptomeningeal metastases (carcinomatous meningitis) or...
- Participants must not have any significant cardiovascular impairment as evidenced by uncontrolled hypertension (despite optimal medical treatment)...
- Participants must not an active autoimmune disease.
- Other protocol-defined Inclusion/Exclusion criteria apply.
The study team makes the final eligibility decision.
Where it's taking place
- Daphne, Alabama, United States
- Bullhead City, Arizona, United States
- Glendale, Arizona, United States
- Anaheim, California, United States
- Beverly Hills, California, United States
- Fountain Valley, California, United States
- Los Alamitos, California, United States
- Los Angeles, California, United States
- Oakland, California, United States
- Pleasant Hill, California, United States
- Walnut Creek, California, United States
- Lakewood, Colorado, United States
- Clermont, Florida, United States
- Coral Springs, Florida, United States
- Hialeah, Florida, United States
- Tamarac, Florida, United States
- Athens, Georgia, United States
- Augusta, Georgia, United States
- Marietta, Georgia, United States
- Urbana, Illinois, United States
+ 235 more site(s).
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Daphne, Alabama, United States; Bullhead City, Arizona, United States; Glendale, Arizona, United States; Anaheim, California, United States; Beverly Hills, California, United States; Fountain Valley, California, United States and 249 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.