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New treatment option for Osteoarthritic Knee Pain
Official title Percutaneous Transcatheter Genicular Embolization in Osteoarthritis
ClinicalTrials.gov ID: NCT07361198
What this study is testing
- What it's testing
- This clinical study investigates a minimally invasive treatment called percutaneous transcatheter embolization of knee arteries for patients with chronic knee pain caused by advanced knee osteoarthritis or persistent pain after total knee replacement. Osteoarthritis of the knee is a common degenerative condition that can lead to long-term pain, reduced mobility, and decreased quality of life, and some patients do not achieve sufficient relief with standard treatments.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 40 to 80
You may be able to join if
- Adults aged 40 to 80 years
- Clinical symptoms consistent with chronic knee pain
- Radiographically confirmed knee osteoarthritis of Kellgren-Lawrence grade II-IV or persistent knee pain following total knee arthroplasty
- Insufficient pain relief after standard conservative treatment (e.g., pharmacological therapy, physical therapy, or injections)
- Ability to understand the study procedures and provide written informed consent \_ Willingness and ability to comply with the study procedures and...
You likely can't join if
- Active local or systemic infection
- Known coagulation disorders or ongoing anticoagulation that cannot be safely interrupted
- Significant peripheral arterial disease affecting the lower limbs
- Known allergy or contraindication to iodinated contrast agents
- Severe renal impairment
- History of fibromyalgia or other generalized chronic pain syndromes that may confound pain assessment
See the full eligibility criteria
- Adults aged 40 to 80 years
- Clinical symptoms consistent with chronic knee pain
- Radiographically confirmed knee osteoarthritis of Kellgren-Lawrence grade II-IV or persistent knee pain following total knee arthroplasty
- Insufficient pain relief after standard conservative treatment (e.g., pharmacological therapy, physical therapy, or injections)
- Ability to understand the study procedures and provide written informed consent \_ Willingness and ability to comply with the study procedures and follow-up schedule
- Active local or systemic infection
- Known coagulation disorders or ongoing anticoagulation that cannot be safely interrupted
- Significant peripheral arterial disease affecting the lower limbs
- Known allergy or contraindication to iodinated contrast agents
- Severe renal impairment
- History of fibromyalgia or other generalized chronic pain syndromes that may confound pain assessment
- Pregnancy or breastfeeding
The study team makes the final eligibility decision.
Where it's taking place
- Ústí nad Labem, Czechia
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 40 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Ústí nad Labem, Czechia. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.