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New treatment option for Patients With Cardiovascular Disease
Official title OCTA in Cardiovascular Disease and Healthy Controls
ClinicalTrials.gov ID: NCT07359664
What this study is testing
- What it's testing
- This prospective clinical study will involve the non-invasive assessment of retinal vessels using OCTA (Cirrus OCT 6000 AngioPlex) and scanning laser Doppler flowmetry (SLDF) in patients with cardiovascular disease and healthy individuals. The study will be conducted at the Clinical Research Centre (CRC), Department of Nephrology and Hypertension at the University of Erlangen-Nuremberg.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 75. Healthy volunteers may be eligible.
You may be able to join if
- for patients with cardiovascular disease:
- cardiovascular disease defined as one or more of the following: arterial hypertension, type 2 diabetes mellitus, chronic kidney disease, heart...
- BMI 18-29.9 kg/m2
- Non-smoker
- Good general health, as determined by study personnel based on assessments of previous visits, including anamnesis, vital signs, physical examination...
You likely can't join if
- for patients with cardiovascular disease:
- Active ophthalmological (retinal) disease resulting in impaired visual assessment of retinal vessels (e.g. glaucoma, cataracts, retinal oedema)...
- Active ophthalmological (retinal) disease with reduced visual assessment of retinal vessels (e.g. glaucoma, cataracts, retinal oedema).
- clinically relevant deviation in physical examination, vital signs, or laboratory parameters (based on the physician's clinical judgement).
- a clinically relevant history of cardiovascular disease or any other previously known cardiovascular disease
- History of clinically relevant neurological, gastrointestinal, renal, hepatic, psychological, pulmonary, metabolic, endocrine or other diseases
See the full eligibility criteria
- for patients with cardiovascular disease:
- cardiovascular disease defined as one or more of the following: arterial hypertension, type 2 diabetes mellitus, chronic kidney disease, heart failure for healthy individuals:
- BMI 18-29.9 kg/m2
- Non-smoker
- Good general health, as determined by study personnel based on assessments of previous visits, including anamnesis, vital signs, physical examination and clinical laboratory parameters.
- for patients with cardiovascular disease:
- Active ophthalmological (retinal) disease resulting in impaired visual assessment of retinal vessels (e.g. glaucoma, cataracts, retinal oedema). Exclusion criteria for healthy individuals:
- Active ophthalmological (retinal) disease with reduced visual assessment of retinal vessels (e.g. glaucoma, cataracts, retinal oedema).
- clinically relevant deviation in physical examination, vital signs, or laboratory parameters (based on the physician's clinical judgement).
- a clinically relevant history of cardiovascular disease or any other previously known cardiovascular disease
- History of clinically relevant neurological, gastrointestinal, renal, hepatic, psychological, pulmonary, metabolic, endocrine or other diseases
- office blood pressure above or equal to 140/90 mmHg
- Office heart rate outside of the following range: 50-99 bpm
- regular intake of any medication for the treatment of cardiovascular diseases (e.g. antihypertensive or antidiabetic medication) within one month before study inclusion
- alcohol or drug abuse
The study team makes the final eligibility decision.
Where it's taking place
- Erlangen, Bavaria, Germany
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 75 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Erlangen, Bavaria, Germany. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.