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New treatment option for PARKINSON DISEASE (Disorder)
Official title Understanding How Movements Are Transferred From Task to Task in Parkinson's Disease
ClinicalTrials.gov ID: NCT07351032
What this study is testing
- What it's testing
- The purpose of this study is to understand how a specific brain area, the Posterior Parietal Cortex (PPC), plays a role in movement transfer from walking on a split-belt treadmill (SBT) to walking on the ground in people with Parkinson's disease (PwPD). Here, investigators will apply repeated transcranial magnetic stimulation (rTMS) to upregulate the PPC.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 50 and older
You may be able to join if
- a confirmed diagnosis of idiopathic Parkinson's disease
- absence of freezing of gait confirmed by a "No" answer to the second item of the New Freezing of Gait Questionnaire (NFOGQ) and no observation of FOG...
- no other neurological diagnosis
- no severe musculoskeletal/orthopedic or vestibular condition that interferes with walking and or significantly affects balance
- no mild cognitive impairment (Montreal Cognitive Assessment ≥ 25)
You likely can't join if
- severe dyskinesia that interacts with walking and balance hearing or visual impairment
- observed inability to walk safely on a tied-belt treadmill
- neurological disorders other than PD or other pathology (e.g., orthopedic) interfering with mobility. - contradiction for TMS
- implanted deep brain stimulator.
See the full eligibility criteria
- a confirmed diagnosis of idiopathic Parkinson's disease
- absence of freezing of gait confirmed by a "No" answer to the second item of the New Freezing of Gait Questionnaire (NFOGQ) and no observation of FOG during a freezing provoking test
- no other neurological diagnosis
- no severe musculoskeletal/orthopedic or vestibular condition that interferes with walking and or significantly affects balance
- no mild cognitive impairment (Montreal Cognitive Assessment ≥ 25)
- able to walk independently and without assistive device for 30 minutes
- no previous experience with split-belt treadmill.
- severe dyskinesia that interacts with walking and balance hearing or visual impairment
- observed inability to walk safely on a tied-belt treadmill
- neurological disorders other than PD or other pathology (e.g., orthopedic) interfering with mobility. - contradiction for TMS
- implanted deep brain stimulator.
The study team makes the final eligibility decision.
Where it's taking place
- Montreal, Quebec, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 50 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Montreal, Quebec, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.