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New treatment option for Osteo Arthritis of the Knee
Official title Combination of Nerve Blocks and Local Infiltration Analgesia in Knee Arthroplasty
ClinicalTrials.gov ID: NCT07350252
What this study is testing
What is Ropivacain 5 mg/ml + Clonidine?
Ropivacain 5 mg/ml + Clonidine is an investigational medicine, given as an injection under the skin, being studied as a potential treatment for osteo arthritis of the knee.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The aim of this clinical randomized trial is to compare local infiltration analgesia (LIA) alone versus the combination of LIA with saphenous nerve (SN) block, block of the nerve to vastus medialis (NVM), and anterior femoral cutaneous nerve (AFCN) block in participants undergoing total knee arthroplasty (TKA). The primary outcome is pain intensity, measured using the Numerical Rating Scale (NRS) at multiple time points after surgery.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- -Undergoing primary unilateral total knee arthroplasty
You likely can't join if
- Pregnancy
- Coagulopathy or other bleeding disorder that precludes regional anesthesia
- Allergy to local anesthetics
- Inability to understand spoken and written Swedish
- Unwillingness to participate in the study
The study team makes the final eligibility decision.
Where it's taking place
- Trelleborg, Sweden
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Trelleborg, Sweden. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.