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Compares treatment options for Oral Melatonin
Official title Oral Melatonin Versus Nebulized Dexmedetomidine on Emergence Agitation in Children Undergoing Adenotonsillectomy
ClinicalTrials.gov ID: NCT07345715
What this study is testing
What is Normal saline?
Normal saline is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for oral melatonin.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study aims to compare the efficacy of using oral Melatonin versus nebulized Dexmedetomidine in limitation of emergence agitation in children undergoing adenotonsillectomy.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 3 to 7
You may be able to join if
- Children aged between 3 and 7 years.
- Both sexes.
- Classified as American Society of Anesthesiologists (ASA) physical status I or II according to the American Society of Anesthesiologists.
- Scheduled for elective adenotonsillectomy under general anesthesia.
You likely can't join if
- Parental refusal to participate in the study.
- Known allergy or hypersensitivity to dexmedetomidine, melatonin or midazolam.
- Presence of developmental delay.
- Central nervous system disorders.
- Intellectual disability (formerly termed mental retardation).
- Neurological or psychiatric conditions associated with anxiety or agitation (e.g., cerebral palsy, epilepsy, separation anxiety disorder...
See the full eligibility criteria
- Children aged between 3 and 7 years.
- Both sexes.
- Classified as American Society of Anesthesiologists (ASA) physical status I or II according to the American Society of Anesthesiologists.
- Scheduled for elective adenotonsillectomy under general anesthesia.
- Parental refusal to participate in the study.
- Known allergy or hypersensitivity to dexmedetomidine, melatonin or midazolam.
- Presence of developmental delay.
- Central nervous system disorders.
- Intellectual disability (formerly termed mental retardation).
- Neurological or psychiatric conditions associated with anxiety or agitation (e.g., cerebral palsy, epilepsy, separation anxiety disorder, attention-deficit/hyperactivity disorder).
- Current or recent treatment with anticonvulsants or sedative medications
The study team makes the final eligibility decision.
Where it's taking place
- Tanta, El-Gharbia, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 3 years to 7 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Tanta, El-Gharbia, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.