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Compares treatment options for Oral
Official title Oral Melatonin Versus Oral Pregabalin on Postoperative Pain and Anxiety Following Spine Surgery
ClinicalTrials.gov ID: NCT07344467
What this study is testing
What is Melatonin capsule?
Melatonin capsule is an investigational medicine, given as an once-daily pill taken by mouth, being studied as a potential treatment for oral.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study aims to compare the efficacy of using Melatonin versus Pregabalin on postoperative pain and anxiety after spine surgeries.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 21 to 60
You may be able to join if
- Patients aged 21-60 years old.
- Both sexes.
- Patients of American Society of Anesthesiologists (ASA) physical status I \& II.
- Undergoing elective spine surgery.
You likely can't join if
- Patient refusal.
- History of allergic reactions to melatonin or pregabalin.
- Patients with cardiovascular disease (ischemic heart disease, Heart Failure, Arrythmia, Heart Block).
- Patients with kidney disease with (plasma creatinine level \> 1.5mg/dl).
- Patients with liver disease with (aspartate transaminase, alanine transaminase, and bilirubin levels more than twice the upper limit of normal).
- Psychological and cognitive disorders; dementia; major depression.
See the full eligibility criteria
- Patients aged 21-60 years old.
- Both sexes.
- Patients of American Society of Anesthesiologists (ASA) physical status I \& II.
- Undergoing elective spine surgery.
- Patient refusal.
- History of allergic reactions to melatonin or pregabalin.
- Patients with cardiovascular disease (ischemic heart disease, Heart Failure, Arrythmia, Heart Block).
- Patients with kidney disease with (plasma creatinine level \> 1.5mg/dl).
- Patients with liver disease with (aspartate transaminase, alanine transaminase, and bilirubin levels more than twice the upper limit of normal).
- Psychological and cognitive disorders; dementia; major depression.
- Circadian rhythm disorders such as chronic fatigue syndrome and drowsiness.
The study team makes the final eligibility decision.
Where it's taking place
- Tanta, El-Gharbia, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 21 years to 60 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Tanta, El-Gharbia, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.