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New treatment option for Airway Management
Official title The 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During Anesthesia Induction
ClinicalTrials.gov ID: NCT07340255
What this study is testing
- What it's testing
- Exploring the 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During Anesthesia Induction: The aim is to determine the optimal ventilation pressure for esophageal insufflation avoidance during anesthesia induction and to explore its guiding significance for anesthesia management. The goal is to provide a more precise and personalized ventilation pressure setting standard for clinical anesthesia, thereby enhancing the safety of the anesthesia induction phase.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- Age: 18-65 years, regardless of gender;
- ASA classification: I-III;
- Scheduled for elective general anesthesia surgery;
- BMI: 18.0-28.0 kg/m²;
- Preoperative fasting: Solid food \>6 hours, liquid \>2 hours;
You likely can't join if
- Pregnant or breastfeeding women;
- History of upper gastrointestinal diseases such as gastroesophageal reflux disease, peptic ulcers, or hiatal hernia;
- Recent (within 2 weeks) respiratory infections, chronic cough, similar symptoms, and other known or predictable respiratory system diseases;
- Need for emergency surgery or airway obstruction after anesthesia induction requiring urgent intubation;
- Inability to achieve adequate oxygenation during mask ventilation (e.g., SpO₂ \< 92% for 30 seconds, unresponsive to treatment);
- History of contraindications or allergies to study medications;
See the full eligibility criteria
- Age: 18-65 years, regardless of gender;
- ASA classification: I-III;
- Scheduled for elective general anesthesia surgery;
- BMI: 18.0-28.0 kg/m²;
- Preoperative fasting: Solid food \>6 hours, liquid \>2 hours;
- Less than two from five criteria predicting difficult mask ventilation as described by Langeron et al.(Prediction of difficult mask ventilation. Anesthesiology 2000; 92:1229-36);
- No severe underlying conditions such as heart, lung, liver, or kidney disease;
- Signed informed consent and ability to cooperate with the study protocol.
- Pregnant or breastfeeding women;
- History of upper gastrointestinal diseases such as gastroesophageal reflux disease, peptic ulcers, or hiatal hernia;
- Recent (within 2 weeks) respiratory infections, chronic cough, similar symptoms, and other known or predictable respiratory system diseases;
- Need for emergency surgery or airway obstruction after anesthesia induction requiring urgent intubation;
- Inability to achieve adequate oxygenation during mask ventilation (e.g., SpO₂ \< 92% for 30 seconds, unresponsive to treatment);
- History of contraindications or allergies to study medications;
- Inability to understand the study content or refusal to cooperate;
- Oropharyngeal or facial pathology;
- with an indwelling gastric tube, and who had previously undergone gastric surgery.
The study team makes the final eligibility decision.
Where it's taking place
- Jiaxing, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Jiaxing, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.